Articles dans des revues avec comité de lecture (169)
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Soumoy, L., Schepkens, C., Krayem, M., Najem, A., Tagliatti, V., Ghanem, G. E., Saussez, S., Colet, J.-M., & Journé, F. (2020). Metabolic reprogramming in metastatic melanoma with acquired resistance to targeted therapies: Integrative metabolomic and proteomic analysis. Cancers (Basel), 12(5), 1323. doi:10.3390/cancers1205132321.
Krayem, M., Aftimos, P., Najem, A., van den Hooven, T., van den Berg, A., Hovestad-Bijl, L., de Wijn, R., Hilhorst, R., Ruijtenbeek, R., Sabbah, M., Kerger, J., Awada, A., Journé, F., & Ghanem, G. E. (2020). Kinome Profiling to Predict Sensitivity to MAPK Inhibition in Melanoma and to Provide New Insights into Intrinsic and Acquired Mechanism of Resistance Short Title: Sensitivity Prediction to MAPK Inhibitors in Melanoma. Cancers (Basel), 12(2). doi:10.3390/cancers1202051222.
Krayem, M., Sabbah, M., Najem, A., Wouters, A., Lardon, F., Simon, S., Sales, F., Journé, F., Awada, A., Ghanem, G. E., & Van Gestel, D. (2019). The benefit of reactivating p53 under MAPK inhibition on the efficacy of radiotherapy in melanoma. Cancers (Basel), 11(8), 1093. doi:10.3390/cancers1108109323.
Soumoy, L., Kindt, N., Ghanem, G. E., Saussez, S., & Journé, F. (2019). Role of macrophage migration inhibitory factor (Mif) in melanoma. Cancers (Basel), 11(4), 529. doi:10.3390/cancers1104052924.
Krayem, M., Najem, A., Journé, F., Morandini, R., Sales, F., Awada, A., & Ghanem, G. E. (2018). Acquired resistance to BRAFi reverses senescence-like phenotype in mutant BRAF melanoma. Oncotarget, 9(61), 31888-31903. doi:10.18632/oncotarget.2587925.
Perdrix, A., Najem, A., Saussez, S., Awada, A., Journé, F., Ghanem, G. E., & Krayem, M. (2017). PRIMA-1 and PRIMA-1Met (APR-246): From mutant/wild type p53 reactivation to unexpected mechanisms underlying their potent anti-tumor effect in combinatorial therapies. Cancers (Basel), 9(12), 172. doi:10.3390/cancers912017227.
Najem, A., Krayem, M., Perdrix, A., Kerger, J., Awada, A., Journé, F., & Ghanem, G. E. (2017). New drug combination strategies in melanoma: Current status and future directions. Anticancer research, 37(11), 5941-5953. doi:10.21873/anticanres.1204128.
Gilot, D., Migault, M., Bachelot, L., Journé, F., Rogiers, A., Donnou-Fournet, E., Mogha, A., Mouchet, N., Pinel-Marie, M. L., Mari, B., Montier, T., Correia, S., Gautron, A., Rambow, F., El Hajj, P., Ben Jouira, R., Tartare-Deckert, S., Marine, J.-C., Felden, B., Ghanem, G. E., & Galibert, M. D. (2017). A non-coding function of TYRP1 mRNA promotes melanoma growth. Nature cell biology, 19(11), 1348-1357. doi:10.1038/ncb362329.
Zhang, Y., Guo, J., Yang, W., Goncalves, C., Rzymski, T., Dreas, A., Zyłkiewicz, E., Mikulski, M., Brzózka, K., Golas, A., Kong, Y., Ma, M., Huang, F., Huor, B., Guo, Q., Da Silva, S. D., Rivera-Torres, J., Cai, Y., Topisirovic, I., Su, J., Bijian, K., Alaoui-Jamali, M. A., Huang, S., Journé, F., Ghanem, G. E., Miller, W. W., & Del Rincón, S. S. (2017). MNK1/2 inhibition limits oncogenicity and metastasis of KIT-mutant melanoma. The Journal of clinical investigation, 127(11), 4179-4192. doi:10.1172/JCI9125830.
Najem, A., Krayem, M., Sales, F., Hussein, N., Badran, B., Robert, C., Awada, A., Journé, F., & Ghanem, G. E. (2017). P53 and MITF/Bcl-2 identified as key pathways in the acquired resistance of NRAS-mutant melanoma to MEK inhibition. European journal of cancer, 83, 154-165. doi:10.1016/j.ejca.2017.06.03331.
Wimana, Z., Ghanem, G. E., Gebhart, G., Guiot, T., Vanderlinden, B., Larsimont, D., Doumont, G., Van Simaeys, G., Goldman, S., & Flamen, P. (2017). N-Acetylcysteine breaks resistance to trastuzumab caused by MUC4 overexpression in human HER2 positive BC-bearing nude mice monitored by 89Zr-Trastuzumab and 18F-FDG PET imaging. Oncotarget, 8(34), 56185-56198. doi:10.18632/oncotarget.17015