Articles dans des revues avec comité de lecture (34)
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Sabbah, M., Krayem, M., Najem, A., Sales, F., Miller, W. W., Del Rincón, S. S., Awada, A., Ghanem, G. E., & Journé, F. (2021). Dasatinib stimulates its own mechanism of resistance by activating a CRTC3/MITF/Bcl-2 pathway in melanoma with mutant or amplified c-kit. Molecular cancer research, 19(7), 1221-1233. doi:10.1158/1541-7786.MCR-20-104014.
Jeschke, J., Collignon, E., Al Wardi, C., Krayem, M., Bizet, M., Jia, Y., Garaud, S., Wimana, Z., Calonne, E., Hassabi, B., Morandini, R., Deplus, R., Putmans, P., Dube, G., Singh, N. K., Koch, A., Shostak, K., Rizzotto, L., Ross, R. L., Desmedt, C., Bareche, Y., Rothé, F., Lehmann-Che, J., Duterque-Coquillaud, M., Leroy, X., Menschaert, G., Teixeira, L., Guo, M., Limbach, P. A., Close, P., Chariot, A., Leucci, E., Ghanem, G., Yuan, B., Willard-Gallo, K., Sotiriou, C., Marine, J.-C., & Fuks, F. (2021). Downregulation of the FTO m6A RNA demethylase promotes EMT-mediated progression of epithelial tumors and sensitivity to Wnt inhibitors. Nature Cancer, 2(6), 611-628. doi:10.1038/s43018-021-00223-715.
Sabbah, M., Najem, A., Krayem, M., Awada, A., Journé, F., & Ghanem, G. E. (2021). Rtk inhibitors in melanoma: From bench to bedside. Cancers (Basel), 13(7), 1685. doi:10.3390/cancers1307168516.
Cogels, M., Rouas, R., Ghanem, G. E., Martinive, P., Awada, A., Van Gestel, D., & Krayem, M. (2021). Humanized Mice as a Valuable Pre-Clinical Model for Cancer Immunotherapy Research. Frontiers in oncology, 11, 784947. doi:10.3389/fonc.2021.78494717.
Krayem, M., Aftimos, P., Najem, A., van den Hooven, T., van den Berg, A., Hovestad-Bijl, L., de Wijn, R., Hilhorst, R., Ruijtenbeek, R., Sabbah, M., Kerger, J., Awada, A., Journé, F., & Ghanem, G. E. (2020). Erratum: Krayem, M., et al. Kinome Profiling to Predict Sensitivity to MAPK Inhibition in Melanoma and to Provide New Insights into Intrinsic and Acquired Mechanism of Resistance Short Title. Cancers (Basel), 12(10), 2981, 1-2. doi:10.3390/cancers1210298118.
Soumoy, L., Wells, M., Najem, A., Krayem, M., Ghanem, G. E., Hambÿe, S., Saussez, S., Blankert, B., & Journé, F. (2020). Toad venom antiproliferative activities on metastatic melanoma: Bio-guided fractionation and screening of the compounds of two different venoms. Biology, 9(8), 218, 1-16. doi:10.3390/biology908021819.
Soumoy, L., Schepkens, C., Krayem, M., Najem, A., Tagliatti, V., Ghanem, G. E., Saussez, S., Colet, J.-M., & Journé, F. (2020). Metabolic reprogramming in metastatic melanoma with acquired resistance to targeted therapies: Integrative metabolomic and proteomic analysis. Cancers (Basel), 12(5), 1323. doi:10.3390/cancers1205132320.
Krayem, M., Aftimos, P., Najem, A., van den Hooven, T., van den Berg, A., Hovestad-Bijl, L., de Wijn, R., Hilhorst, R., Ruijtenbeek, R., Sabbah, M., Kerger, J., Awada, A., Journé, F., & Ghanem, G. E. (2020). Kinome Profiling to Predict Sensitivity to MAPK Inhibition in Melanoma and to Provide New Insights into Intrinsic and Acquired Mechanism of Resistance Short Title: Sensitivity Prediction to MAPK Inhibitors in Melanoma. Cancers (Basel), 12(2). doi:10.3390/cancers1202051221.
Krayem, M., Sabbah, M., Najem, A., Wouters, A., Lardon, F., Simon, S., Sales, F., Journé, F., Awada, A., Ghanem, G. E., & Van Gestel, D. (2019). The benefit of reactivating p53 under MAPK inhibition on the efficacy of radiotherapy in melanoma. Cancers (Basel), 11(8), 1093. doi:10.3390/cancers1108109322.
Chi, V. L. D., Garaud, S., De Silva, P., Thibaud, V., Stamatopoulos, B., Berehad, M., Gu-Trantien, C., Krayem, M., Duvillier, H., Lodewyckx, J. N., Willard-Gallo, K., Sibille, C., & Bron, D. (2019). Age-related changes in the BACH2 and PRDM1 genes in lymphocytes from healthy donors and chronic lymphocytic leukemia patients. BMC cancer, 19(1), 81. doi:10.1186/s12885-019-5276-223.
Krayem, M., Najem, A., Journé, F., Morandini, R., Sales, F., Awada, A., & Ghanem, G. E. (2018). Acquired resistance to BRAFi reverses senescence-like phenotype in mutant BRAF melanoma. Oncotarget, 9(61), 31888-31903. doi:10.18632/oncotarget.2587924.
Djehal, A., Krayem, M., Najem, A., Hammoud, H., Cresteil, T., Nebigil, C. C., Wang, D., Yu, P., Bentouhami, E., Atassi, G., & Désaubry, L. (2018). Targeting prohibitin with small molecules to promote melanogenesis and apoptosis in melanoma cells. European journal of medicinal chemistry, 155, 880-888. doi:10.1016/j.ejmech.2018.06.052