Articles dans des revues avec comité de lecture (48)
14.
Chugunov, A. O., Simms, J., Poyner, D. R., Dehouck, Y., Rooman, M., Gilis, D., & Langer, I. (2010). Evidence that interaction between conserved residues in transmembrane helices 2, 3 and 7 are crucial for human VPAC1 receptor activation. Molecular pharmacology, 78(3), 394-401. doi:10.1124/mol.110.06357815.
Langer, I., Tikhonova, I. G., Boulègue, C., Estève, J.-P., Vatinel, S., Ferrand, A., Moroder, L., Robberecht, P., & Fourmy, D. (2009). Evidence for a direct and functional interaction between the regulators of G protein signaling-2 and phosphorylated C terminus of cholecystokinin-2 receptor. Molecular pharmacology, 75(3), 502-513. doi:10.1124/mol.108.05160716.
Langer, I., Leroy, K., Gaspard, N., Brion, J. P., & Robberecht, P. (2008). Cell surface targeting of VPAC1 receptors: evidence for implication of a quality control system and the proteasome. Biochimica et biophysica acta, 1783(9), 1663-1672. doi:10.1016/j.bbamcr.2008.03.01317.
de Maria, S., Metafora, V., Metafora, S., Ravagnan, G., Cartení, M., Pontoni, G., Facchiano, A., Lepretti, M., Severino, B., Caliendo, G., Santagada, V., Langer, I., & Robberecht, P. (2008). Effect of positive charge in VIP 16gamma-glutamyl diamino derivatives on hVPAC1 and hVPAC2 receptor function. Journal of peptide science, 14(1), 102-109. doi:10.1002/psc.92518.
Foucaud, M., Archer-Lahlou, E., Marco, E., Tikhonova, I. G., Maigret, B., Escrieut, C., Langer, I., & Fourmy, D. (2008). Insights into the binding and activation sites of the receptors for cholecystokinin and gastrin. Regulatory peptides, 145(1-3), 17-23. doi:10.1016/j.regpep.2007.09.02419.
Marco, E., Foucaud, M., Langer, I., Escrieut, C., Tikhonova, I. G., & Fourmy, D. (2007). Mechanism of activation of a G protein-coupled receptor, the human cholecystokinin-2 receptor. The Journal of biological chemistry, 282(39), 28779-28790. doi:10.1074/jbc.M70034920021.
Tikhonova, I. G., Marco, E., Lahlou-Archer, E., Langer, I., Foucaud, M., Maigret, B., & Fourmy, D. (2007). Validated ligand binding sites in CCK receptors. next step: computer-aided design of novel CCK ligands. Current topics in medicinal chemistry, 7(12), 1243-1247.22.
Nachtergael, I., Gaspard, N., Langlet, C., Robberecht, P., & Langer, I. (2006). Asn229 in the third helix of VPAC1 receptor is essential for receptor activation but not for receptor phosphorylation and internalization: comparison with Asn216 in VPAC2 receptor. Cellular signalling, 18(12), 2121-2130. doi:10.1016/j.cellsig.2006.03.006