Articles dans des revues avec comité de lecture (67)
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Oerum, S., Catala, M., Atdjian, C., Brachet, F., Ponchon, L., Barraud, P., Iannazzo, L., Droogmans, L., Braud, E., Ethève-Quelquejeu, M., & Tisné, C. (2019). Bisubstrate analogues as structural tools to investigate m6A methyltransferase active sites. RNA biology, 16(6), 798-808. doi:10.1080/15476286.2019.158936010.
Singh, R. K., Feller, A., Roovers, M., Van Elder, D., Wauters, L., Droogmans, L., & Versées, W. (2018). Structural and biochemical analysis of the dual-specificity Trm10 enzyme from Thermococcus kodakaraensis prompts reconsideration of its catalytic mechanism. RNA, 24(8), 1080-1092. doi:10.1261/rna.064345.11711.
Oerum, S., Roovers, M., Rambo, R. R., Kopec, J., Bailey, H. H., Fitzpatrick, F., Newman, J. J., Newman, W. W., Amberger, A., Zschocke, J., Droogmans, L., Oppermann, U., & Yue, W. W. (2018). Structural insight into the human mitochondrial tRNA purine N1-methyltransferase and ribonuclease P complexes. The Journal of biological chemistry, 293(33), 12862-12876. doi:10.1074/jbc.RA117.00128612.
Oerum, S., Droogmans, L., Oppermann, U., Sass, J. O., Yue, W. W., Roovers, M., Leichsenring, M., Acquaviva-Bourdain, C., Beermann, F., Gemperle-Britschgi, C., Fouilhoux, A., Korwitz-Reichelt, A., & Bailey, H. H. (2017). Novel patient missense mutations in the HSD17B10 gene affect dehydrogenase and mitochondrial tRNA modification functions of the encoded protein. Biochimica et biophysica acta. Molecular basis of disease, 1863(12), 3294-3302. doi:10.1016/j.bbadis.2017.09.00213.
Jurenas, D., Chatterjee, S., Konijnenberg, A., Sobott, F., Droogmans, L., Garcia-Pino, A., & Van Melderen, L. (2017). AtaT blocks translation by N-acetylation of the initiator tRNA-fMet. Nature Chemical Biology. doi:10.1038/nchembio.234614.
Van Laer, B., Droogmans, L., Versées, W., Roovers, M., Wauters, L., Kasprzak, J. J., Dyzma, M., Deyaert, E., Singh, R. K., Feller, A., & Bujnicki, J. M. (2016). Structural and functional insights into tRNA binding and adenosine N1-methylation by an archaeal Trm10 homologue. Nucleic acids research, 44(2), 940-953. doi:10.1093/nar/gkv136915.
Somme, J., Van Laer, B., Roovers, M., Steyaert, J., Versées, W., & Droogmans, L. (2014). Characterization of two homologous 2'-O-methyltransferases showing different specificities for their tRNA substrates. RNA, 20(8), 1257-1271. doi:10.1261/rna.044503.11416.
Roovers, M., Oudjama, Y., Fislage, M., Bujnicki, J. M., Versées, W., & Droogmans, L. (2012). The open reading frame TTC1157 of Thermus thermophilus HB27 encodes the methyltransferase forming N²-methylguanosine at position 6 in tRNA. RNA, 18(4), 815-824. doi:10.1261/rna.030411.11117.
Fislage, M., Roovers, M., Tuszynska, I., Bujnicki, J. M., Droogmans, L., & Versées, W. (2012). Crystal structures of the tRNA:m2G6 methyltransferase Trm14/TrmN from two domains of life. Nucleic acids research. doi:10.1093/nar/gks16318.
Fislage, M., Roovers, M., Münnich, S., Droogmans, L., & Versées, W. (2011). Crystallization and preliminary X-ray crystallographic analysis of putative tRNA-modification enzymes from Pyrococcus furiosus and Thermus thermophilus. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online, 67(Pt 11), 1432-1435. doi:10.1107/S174430911103634719.
Kempenaers, M., Roovers, M., Oudjama, Y., Tkaczuk, K. L., Bujnicki, J. M., & Droogmans, L. (2010). New archaeal methyltransferases forming 1-methyladenosine or 1-methyladenosine and 1-methylguanosine at position 9 of tRNA. Nucleic acids research, 38(19), 6533-6543. doi:10.1093/nar/gkq45120.
de Crécy-Lagard, V., Brochier-Armanet, C., Urbonavicius, J., Fernandez, B., Phillips, G., Lyons, B., Noma, A., Alvarez, S., Droogmans, L., Armengaud, J., & Grosjean, H. (2010). Biosynthesis of wyosine derivatives in tRNA: an ancient and highly diverse pathway in Archaea. Molecular biology and evolution, 27(9), 2062-2077. doi:10.1093/molbev/msq096