Articles dans des revues avec comité de lecture (400)
164.
Colli, M. L., Moore, F., Gurzov, E. N., Ortis, F., & Eizirik, D. L. (2010). MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic beta-cell responses to the viral by-product double-stranded RNA. Human molecular genetics, 19(1), 135-146. doi:10.1093/hmg/ddp474165.
Ortis, F., Naamane, N., Flamez, D., Ladrière, L., Moore, F., Andrade Da Cunha, D., Colli, M. L., Thykjaer, T., Thorsen, K., Orntoft, T. F., & Eizirik, D. L. (2010). Cytokines interleukin-1beta and tumor necrosis factor-alpha regulate different transcriptional and alternative splicing networks in primary beta-cells. Diabetes (New York, N.Y.), 59(2), 358-374. doi:10.2337/db09-1159166.
Ladrière, L., Igoillo Esteve, M., Andrade Da Cunha, D., Brion, J. P., Bugliani, M., Marchetti, P., Eizirik, D. L., & Cnop, M. (2010). Enhanced signaling downstream of ribonucleic Acid-activated protein kinase-like endoplasmic reticulum kinase potentiates lipotoxic endoplasmic reticulum stress in human islets. The Journal of clinical endocrinology and metabolism, 95(3), 1442-1449. doi:10.1210/jc.2009-2322167.
Flamez, D., Roland, I., Berton, A., Kutlu, B., Dufrane, D., Beckers, M. C., De Waele, E., Rooman, I., Bouwens, L., Clark, A., Lonneux, M., Jamar, J. F., Goldman, S., Marechal, D., Goodman, N., Gianello, P., Van Huffel, C., Salmon, I., & Eizirik, D. L. (2010). A genomic-based approach identifies FXYD domain containing ion transport regulator 2 (FXYD2)gamma as a pancreatic beta cell-specific biomarker. Diabetologia, 53(7), 1372-1383. doi:10.1007/s00125-010-1714-z168.
Bouckenooghe, T., Flamez, D., Ortis, F., Goldman, S., & Eizirik, D. L. (2010). Identification of new pancreatic Beta cell targets for in vivo imaging by a systems biology approach. Current pharmaceutical design, 16(14), 1609-1618. doi:10.2174/138161210791164117169.
Jiang, L., Allagnat, F., Nguidjoe, E., Kamagate, A., Pachera, N., Vanderwinden, J.-M., Brini, M., Carafoli, E., Eizirik, D. L., Cardozo, A. K., & Herchuelz, A. (2010). Plasma membrane Ca2+-ATPase overexpression depletes both mitochondrial and endoplasmic reticulum Ca2+ stores and triggers apoptosis in insulin-secreting BRIN-BD11 cells. The Journal of biological chemistry, 285(40), 30634-30643. doi:10.1074/jbc.M110.116681170.
Allagnat, F., Christulia, F., Ortis, F., Pirot, P., Lortz, S., Lenzen, S., Eizirik, D. L., & Cardozo, A. K. (2010). Sustained production of spliced X-box binding protein 1 (XBP1) induces pancreatic beta cell dysfunction and apoptosis. Diabetologia, 53(6), 1120-1130. doi:10.1007/s00125-010-1699-7171.
D'Hertog, W., Maris, M., Ferreira, G. B., Verdrengh, E., Lage, K., Hansen, D. A., Cardozo, A. K., Workman, C., Moreau, Y., Eizirik, D. L., Waelkens, E., Overbergh, L., & Mathieu, C. (2010). Novel insights into the global proteome responses of insulin-producing INS-1E cells to different degrees of endoplasmic reticulum stress. Journal of proteome research, 9(10), 5142-5152. doi:10.1021/pr1004086172.
Igoillo Esteve, M., Marselli, L., Andrade Da Cunha, D., Ladrière, L., Ortis, F., Grieco, F. A., Dotta, F., Weir, G., Marchetti, P., Eizirik, D. L., & Cnop, M. (2010). Palmitate induces a pro-inflammatory response in human pancreatic islets that mimics CCL2 expression by beta cells in type 2 diabetes. Diabetologia, 53(7), 1395-1405. doi:10.1007/s00125-010-1707-y173.
Liechti, R., Csárdi, G., Bergmann, S., Schütz, F., Sengstag, T., Boj, S. F., Servitja, J.-M., Ferrer, J., Van Lommel, L., Schuit, F., Klinger, S., Thorens, B., Naamane, N., Eizirik, D. L., Marselli, L., Bugliani, M., Marchetti, P., Lucas, S., Holm, C., Jongeneel, C. V., & Xenarios, I. (2010). EuroDia: a beta-cell gene expression resource. Database : the journal of biological databases and curation, 2010, baq024. doi:10.1093/database/baq024174.
Andrade Da Cunha, D., Ladrière, L., Ortis, F., Igoillo Esteve, M., Gurzov, E. N., Lupi, R., Marchetti, P., Eizirik, D., & Cnop, M. (2009). Glucagon-like peptide-1 agonists protect pancreatic beta-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB. Diabetes (New York, N.Y.), 58(12), 2851-2862. doi:10.2337/db09-0685175.
Moore, F., Colli, M. L., Cnop, M., Igoillo Esteve, M., Cardozo, A. K., Andrade Da Cunha, D., Bugliani, M., Marchetti, P., & Eizirik, D. (2009). PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis. Diabetes (New York, N.Y.), 58(6), 1283-1291. doi:10.2337/db08-1510