Peer-reviewed journal articles (66)

  1. 49. Moore, F., Santin Gomez, I., Nogueira, T. C., Gurzov, E. N., Marselli, L., Marchetti, P., & Eizirik, D. L. (2012). The transcription factor C/EBP delta has anti-apoptotic and anti-inflammatory roles in pancreatic beta cells. PloS one, 7(2), e31062. doi:10.1371/journal.pone.0031062
  2. 50. Colli, M. L., Nogueira, T. C., Allagnat, F., Andrade Da Cunha, D., Gurzov, E. N., Cardozo, A. K., Roivainen, M., Op De Beeck, A., & Eizirik, D. L. (2011). Exposure to the Viral By-Product dsRNA or Coxsackievirus B5 Triggers Pancreatic Beta Cell Apoptosis via a Bim / Mcl-1 Imbalance. P L o S Pathogens, 7(9), 1002267. doi:10.1371/journal.ppat.1002267
  3. 51. Gurzov, E. N., & Eizirik, D. L. (2011). Bcl-2 proteins in diabetes: mitochondrial pathways of beta-cell death and dysfunction. Trends in cell biology, 21(7), 424-431. doi:10.1016/j.tcb.2011.03.001
  4. 52. Barthson, J., Germano, C. M. R. C., Moore, F., Maida, A., Drucker, D. J., Marchetti, P., Gysemans, C., Mathieu, C., Nuñez, G., Jurisicova, A., Eizirik, D. L., & Gurzov, E. N. (2011). Cytokines tumor necrosis factor-alpha and interferon-gamma induce pancreatic beta-cell apoptosis through STAT1-mediated Bim protein activation. The Journal of biological chemistry, 286(45), 39632-39643. doi:10.1074/jbc.M111.253591
  5. 53. Arif, S., Moore, F., Marks, K., Bouckenooghe, T., Dayan, C. M., Planas, R., Vives-Pi, M., Powrie, J., Tree, T., Marchetti, P., Huang, G. C., Gurzov, E. N., Pujol-Borrell, R., Eizirik, D. L., & Peakman, M. (2011). Peripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated beta-cell death. Diabetes (New York, N.Y.), 60(8), 2112-2119. doi:10.2337/db10-1643
  6. 54. Santin Gomez, I., Moore, F., Colli, M. L., Gurzov, E. N., Marselli, L., Marchetti, P., & Eizirik, D. L. (2011). PTPN2, a candidate gene for type 1 diabetes, modulates pancreatic bata-cell apoptosis via regulation of the BH3-only protein Bim. Diabetes (New York, N.Y.), 60(12), 3279-3288. doi:10.2337/db11-0758
  7. 55. Moore, F., Naamane, N., Colli, M. L., Bouckenooghe, T., Ortis, F., Gurzov, E. N., Igoillo Esteve, M., Mathieu, C., Bontempi, G., Thykjaer, T., Ørntoft, T., & Eizirik, D. L. (2011). STAT1 is a master regulator of pancreatic beta-cell apoptosis and islet inflammation. The Journal of biological chemistry, 286, 929-41.
  8. 56. Igoillo Esteve, M., Gurzov, E. N., Eizirik, D. L., & Cnop, M. (2011). The transcription factor B-cell lymphoma (BCL)-6 modulates pancreatic beta-cell inflammatory responses. Endocrinology, 152(2), 447-456.
  9. 57. Gurzov, E. N., Germano, C. M. R. C., Andrade Da Cunha, D., Ortis, F., Vanderwinden, J.-M., Marchetti, P., Zhang, L., & Eizirik, D. L. (2010). p53 up-regulated modulator of apoptosis (PUMA) activation contributes to pancreatic beta-cell apoptosis induced by proinflammatory cytokines and endoplasmic reticulum stress. The Journal of biological chemistry, 285(26), 19910-19920. doi:10.1074/jbc.M110.122374
  10. 58. Colli, M. L., Moore, F., Gurzov, E. N., Ortis, F., & Eizirik, D. L. (2010). MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic beta-cell responses to the viral by-product double-stranded RNA. Human molecular genetics, 19(1), 135-146. doi:10.1093/hmg/ddp474
  11. 59. Andrade Da Cunha, D., Ladrière, L., Ortis, F., Igoillo Esteve, M., Gurzov, E. N., Lupi, R., Marchetti, P., Eizirik, D., & Cnop, M. (2009). Glucagon-like peptide-1 agonists protect pancreatic beta-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB. Diabetes (New York, N.Y.), 58(12), 2851-2862. doi:10.2337/db09-0685
  12. 60. Gurzov, E. N., Ortis, F., Andrade Da Cunha, D., Gosset, G., Li, M., Cardozo, A. K., & Eizirik, D. L. (2009). Signaling by IL-1beta+IFN-gamma and ER stress converge on DP5/Hrk activation: a novel mechanism for pancreatic beta-cell apoptosis. Cell death and differentiation, 16(11), 1539-1550. doi:10.1038/cdd.2009.99

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