Peer-reviewed journal articles (66)

  1. 25. Stanley, W. W., Trivedi, P. P., Sutherland, A. A., Thomas, H. H., & Gurzov, E. N. (2017). Differential regulation of pro-inflammatory cytokine signalling by protein tyrosine phosphatases in pancreatic beta-cells. Journal of molecular endocrinology, 59(4), 325-337. doi:10.1530/JME-17-0089
  2. 26. Pilkington, E. H., Lai, M., Ge, X., Stanley, W. J., Wang, B., Wang, M., Kakinen, A., Sani, M.-A., Whittaker, M. M., Gurzov, E. N., Ding, F., Quinn, J. J., Davis, T. P., & Ke, P. C. (2017). Star Polymers Reduce Islet Amyloid Polypeptide Toxicity via Accelerated Amyloid Aggregation. Biomacromolecules. doi:10.1021/acs.biomac.7b01301
  3. 27. Wali, J. A., Galic, S., Tan, C. Y., Gurzov, E. N., Frazier, A. A., Connor, T., Ge, J., Pappas, E. G., Stroud, D., Varanasi, C. L., Selck, C., Ryan, M. T., Thorburn, D. D., Kemp, B. E., Krishnamurthy, B., Kay, T. W., McGee, S. S., & Thomas, H. H. (2017). Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice. Cell death and differentiation. doi:10.1038/cdd.2017.168
  4. 28. Litwak, S. A., Pang, L., Galic, S., Igoillo Esteve, M., Stanley, W. J., Turatsinze, J. V., Loh, K., Thomas, H. H., Sharma, A., Trepo, E., Moreno, C., Gough, D. J., Eizirik, D., de Haan, J. B., & Gurzov, E. N. (2017). JNK Activation of BIM Promotes Hepatic Oxidative Stress, Steatosis and Insulin Resistance in Obesity. Diabetes (New York, N.Y.). doi:10.2337/db17-0348
  5. 29. Loh, K., Shi, Y.-C., Walters, S., Bensellam, M., Lee, K., Dezaki, K., Nakata, M., Ip, C. K., Chan, J. Y., Gurzov, E. N., Thomas, H. H., Waibel, M., Cantley, J., Kay, T. W., Yada, T., Laybutt, R. D., Grey, S. S., & Herzog, H. (2017). Inhibition of Y1 receptor signaling improves islet transplant outcome. Nature communications, 8(1), 490. doi:10.1038/s41467-017-00624-2
  6. 30. Ge, X., Kakinen, A., Gurzov, E. N., Yang, W., Pang, L., Pilkington, E. H., Nedumpully-Govindan, P., Chen, P., Separovic, F., Davis, T. P., Ke, P. C., & Ding, F. (2017). Zinc-coordination and C-peptide complexation: a potential mechanism for the endogenous inhibition of IAPP aggregation. Chemical communications, 53(68), 9394-9397. doi:10.1039/c7cc04291d
  7. 31. Gurzov, E. N., Stanley, W. J., Pappas, E. G., Thomas, H. H., & Gough, D. D. (2016). The JAK/STAT pathway in obesity and diabetes. The FEBS journal, 283(16), 3002-3015. doi:10.1111/febs.13709
  8. 32. Jhala, G., Chee, J., Trivedi, P. M., Selck, C., Gurzov, E. N., Graham, K. L., Thomas, H. H., Kay, T. W. H. T., & Krishnamurthy, B. (2016). Perinatal tolerance to proinsulin is sufficient to prevent autoimmune diabetes. JCI insight, 1(10), e86065. doi:10.1172/jci.insight.86065
  9. 33. Litwak, S. A., Loh, K., Stanley, W. J., Pappas, E. G., Wali, J. A., Selck, C., Strasser, A., Thomas, H. H., & Gurzov, E. N. (2016). p53-upregulated-modulator-of-apoptosis (PUMA) deficiency affects food intake but does not impact on body weight or glucose homeostasis in diet-induced obesity. Scientific reports, 6, 23802. doi:10.1038/srep23802
  10. 34. Gurzov, E. N., Wang, B., Pilkington, E. H., Chen, P., Kakinen, A., Stanley, W. J., Litwak, S. A., Hanssen, E. G., Davis, T. P., Ding, F., & Ke, P. C. (2016). Inhibition of hIAPP Amyloid Aggregation and Pancreatic Beta-Cell Toxicity by OH-Terminated PAMAM Dendrimer. Small, 12(12), 1615-1626. doi:10.1002/smll.201502317
  11. 35. Pilkington, E. H., Gurzov, E. N., Kakinen, A., Litwak, S. A., Stanley, W. J., Davis, T. P., & Ke, P. C. (2016). Pancreatic Beta-Cell Membrane Fluidity and Toxicity Induced by Human Islet Amyloid Polypeptide Species. Scientific reports, 6, 21274. doi:10.1038/srep21274
  12. 36. Nedumpully-Govindan, P., Gurzov, E. N., Chen, P., Pilkington, E. E., Stanley, W. J., Litwak, S. A., Davis, T. P., Ke, P. C., & Ding, F. (2016). Graphene oxide inhibits hIAPP amyloid fibrillation and toxicity in insulin-producing NIT-1 cells. PCCP. Physical chemistry chemical physics, 18(1), 94-100. doi:10.1039/c5cp05924k

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