Peer-reviewed journal articles (66)
25.
Stanley, W. W., Trivedi, P. P., Sutherland, A. A., Thomas, H. H., & Gurzov, E. N. (2017). Differential regulation of pro-inflammatory cytokine signalling by protein tyrosine phosphatases in pancreatic beta-cells. Journal of molecular endocrinology, 59(4), 325-337. doi:10.1530/JME-17-008926.
Pilkington, E. H., Lai, M., Ge, X., Stanley, W. J., Wang, B., Wang, M., Kakinen, A., Sani, M.-A., Whittaker, M. M., Gurzov, E. N., Ding, F., Quinn, J. J., Davis, T. P., & Ke, P. C. (2017). Star Polymers Reduce Islet Amyloid Polypeptide Toxicity via Accelerated Amyloid Aggregation. Biomacromolecules. doi:10.1021/acs.biomac.7b0130127.
Wali, J. A., Galic, S., Tan, C. Y., Gurzov, E. N., Frazier, A. A., Connor, T., Ge, J., Pappas, E. G., Stroud, D., Varanasi, C. L., Selck, C., Ryan, M. T., Thorburn, D. D., Kemp, B. E., Krishnamurthy, B., Kay, T. W., McGee, S. S., & Thomas, H. H. (2017). Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice. Cell death and differentiation. doi:10.1038/cdd.2017.16828.
Litwak, S. A., Pang, L., Galic, S., Igoillo Esteve, M., Stanley, W. J., Turatsinze, J. V., Loh, K., Thomas, H. H., Sharma, A., Trepo, E., Moreno, C., Gough, D. J., Eizirik, D., de Haan, J. B., & Gurzov, E. N. (2017). JNK Activation of BIM Promotes Hepatic Oxidative Stress, Steatosis and Insulin Resistance in Obesity. Diabetes (New York, N.Y.). doi:10.2337/db17-034829.
Loh, K., Shi, Y.-C., Walters, S., Bensellam, M., Lee, K., Dezaki, K., Nakata, M., Ip, C. K., Chan, J. Y., Gurzov, E. N., Thomas, H. H., Waibel, M., Cantley, J., Kay, T. W., Yada, T., Laybutt, R. D., Grey, S. S., & Herzog, H. (2017). Inhibition of Y1 receptor signaling improves islet transplant outcome. Nature communications, 8(1), 490. doi:10.1038/s41467-017-00624-230.
Ge, X., Kakinen, A., Gurzov, E. N., Yang, W., Pang, L., Pilkington, E. H., Nedumpully-Govindan, P., Chen, P., Separovic, F., Davis, T. P., Ke, P. C., & Ding, F. (2017). Zinc-coordination and C-peptide complexation: a potential mechanism for the endogenous inhibition of IAPP aggregation. Chemical communications, 53(68), 9394-9397. doi:10.1039/c7cc04291d31.
Gurzov, E. N., Stanley, W. J., Pappas, E. G., Thomas, H. H., & Gough, D. D. (2016). The JAK/STAT pathway in obesity and diabetes. The FEBS journal, 283(16), 3002-3015. doi:10.1111/febs.1370932.
Jhala, G., Chee, J., Trivedi, P. M., Selck, C., Gurzov, E. N., Graham, K. L., Thomas, H. H., Kay, T. W. H. T., & Krishnamurthy, B. (2016). Perinatal tolerance to proinsulin is sufficient to prevent autoimmune diabetes. JCI insight, 1(10), e86065. doi:10.1172/jci.insight.8606533.
Litwak, S. A., Loh, K., Stanley, W. J., Pappas, E. G., Wali, J. A., Selck, C., Strasser, A., Thomas, H. H., & Gurzov, E. N. (2016). p53-upregulated-modulator-of-apoptosis (PUMA) deficiency affects food intake but does not impact on body weight or glucose homeostasis in diet-induced obesity. Scientific reports, 6, 23802. doi:10.1038/srep2380234.
Gurzov, E. N., Wang, B., Pilkington, E. H., Chen, P., Kakinen, A., Stanley, W. J., Litwak, S. A., Hanssen, E. G., Davis, T. P., Ding, F., & Ke, P. C. (2016). Inhibition of hIAPP Amyloid Aggregation and Pancreatic Beta-Cell Toxicity by OH-Terminated PAMAM Dendrimer. Small, 12(12), 1615-1626. doi:10.1002/smll.20150231735.
Pilkington, E. H., Gurzov, E. N., Kakinen, A., Litwak, S. A., Stanley, W. J., Davis, T. P., & Ke, P. C. (2016). Pancreatic Beta-Cell Membrane Fluidity and Toxicity Induced by Human Islet Amyloid Polypeptide Species. Scientific reports, 6, 21274. doi:10.1038/srep2127436.
Nedumpully-Govindan, P., Gurzov, E. N., Chen, P., Pilkington, E. E., Stanley, W. J., Litwak, S. A., Davis, T. P., Ke, P. C., & Ding, F. (2016). Graphene oxide inhibits hIAPP amyloid fibrillation and toxicity in insulin-producing NIT-1 cells. PCCP. Physical chemistry chemical physics, 18(1), 94-100. doi:10.1039/c5cp05924k