Peer-reviewed journal articles (57)
14.
Grohmann, M., Wiede, F., Dodd, G. G., Gurzov, E. N., Ooi, G. G., Butt, T., Rasmiena, A. A., Kaur, S., Gulati, T., Goh, P. P., Treloar, A. A., Archer, S. D., Brown, W. A., Muller, M., Watt, M. J., Ohara, O., McLean, C. A., & Tiganis, T. (2018). Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC. Cell, 175(5), 1289-1306.e20. doi:10.1016/j.cell.2018.09.05316.
Stanley, W. W., Trivedi, P. P., Sutherland, A. A., Thomas, H. H., & Gurzov, E. N. (2017). Differential regulation of pro-inflammatory cytokine signalling by protein tyrosine phosphatases in pancreatic beta-cells. Journal of molecular endocrinology, 59(4), 325-337. doi:10.1530/JME-17-008917.
Pilkington, E. H., Lai, M., Ge, X., Stanley, W. J., Wang, B., Wang, M., Kakinen, A., Sani, M.-A., Whittaker, M. M., Gurzov, E. N., Ding, F., Quinn, J. J., Davis, T. P., & Ke, P. C. (2017). Star Polymers Reduce Islet Amyloid Polypeptide Toxicity via Accelerated Amyloid Aggregation. Biomacromolecules. doi:10.1021/acs.biomac.7b0130118.
Wali, J. A., Galic, S., Tan, C. Y., Gurzov, E. N., Frazier, A. A., Connor, T., Ge, J., Pappas, E. G., Stroud, D., Varanasi, C. L., Selck, C., Ryan, M. T., Thorburn, D. D., Kemp, B. E., Krishnamurthy, B., Kay, T. W., McGee, S. S., & Thomas, H. H. (2017). Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice. Cell death and differentiation. doi:10.1038/cdd.2017.16819.
Litwak, S. A., Pang, L., Galic, S., Igoillo Esteve, M., Stanley, W. J., Turatsinze, J. V., Loh, K., Thomas, H. H., Sharma, A., Trepo, E., Moreno, C., Gough, D. J., Eizirik, D., de Haan, J. B., & Gurzov, E. N. (2017). JNK Activation of BIM Promotes Hepatic Oxidative Stress, Steatosis and Insulin Resistance in Obesity. Diabetes (New York, N.Y.). doi:10.2337/db17-034820.
Loh, K., Shi, Y.-C., Walters, S., Bensellam, M., Lee, K., Dezaki, K., Nakata, M., Ip, C. K., Chan, J. Y., Gurzov, E. N., Thomas, H. H., Waibel, M., Cantley, J., Kay, T. W., Yada, T., Laybutt, R. D., Grey, S. S., & Herzog, H. (2017). Inhibition of Y1 receptor signaling improves islet transplant outcome. Nature communications, 8(1), 490. doi:10.1038/s41467-017-00624-221.
Ge, X., Kakinen, A., Gurzov, E. N., Yang, W., Pang, L., Pilkington, E. H., Nedumpully-Govindan, P., Chen, P., Separovic, F., Davis, T. P., Ke, P. C., & Ding, F. (2017). Zinc-coordination and C-peptide complexation: a potential mechanism for the endogenous inhibition of IAPP aggregation. Chemical communications, 53(68), 9394-9397. doi:10.1039/c7cc04291d22.
Gurzov, E. N., Stanley, W. J., Pappas, E. G., Thomas, H. H., & Gough, D. D. (2016). The JAK/STAT pathway in obesity and diabetes. The FEBS journal, 283(16), 3002-3015. doi:10.1111/febs.1370923.
Jhala, G., Chee, J., Trivedi, P. M., Selck, C., Gurzov, E. N., Graham, K. L., Thomas, H. H., Kay, T. W. H. T., & Krishnamurthy, B. (2016). Perinatal tolerance to proinsulin is sufficient to prevent autoimmune diabetes. JCI insight, 1(10), e86065. doi:10.1172/jci.insight.8606524.
Litwak, S. A., Loh, K., Stanley, W. J., Pappas, E. G., Wali, J. A., Selck, C., Strasser, A., Thomas, H. H., & Gurzov, E. N. (2016). p53-upregulated-modulator-of-apoptosis (PUMA) deficiency affects food intake but does not impact on body weight or glucose homeostasis in diet-induced obesity. Scientific reports, 6, 23802. doi:10.1038/srep23802