About GATA3, HNF3A, and XBP1, three genes co-expressed with the oestrogen receptor-α gene (ESR1) in breast cancer

Lacroix, Marc; Leclercq, Guy

doi:doi/10.1016/j.mce.2004.02.021

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About GATA3, HNF3A, and XBP1, three genes co-expressed with the oestrogen receptor-α gene (ESR1) in breast cancer

par Lacroix, Marc

;Leclercq, Guy

Référence Molecular and cellular endocrinology, 219, 1-2, page (1-7)
Publication Publié, 2004-04

Article révisé par les pairs

Résumé :

In breast tumours and breast cancer cell (BCC) lines, microarray analyses have revealed that a series of genes are expressed in close association with the oestrogen receptor-α (ER-α) gene, ESR1. Three of them, GATA3, HNF3A (also known as FOXA1), and XBP1 encode transcription factors. Here, we present these factors and we discuss their potential involvement in the ER-α-mediated actions in BCC. We notably show the relations that exist, or that might exist, between these factors and the oestrogen-inducible trefoil factor TFF1. © 2004 Elsevier Ireland Ltd. All rights reserved.

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