par Goldman, Michel 
Référence Pathologie et biologie, 51, 2, page (74-75)
Publication Publié, 2003-03
Référence Pathologie et biologie, 51, 2, page (74-75)
Publication Publié, 2003-03
Article révisé par les pairs
| Résumé : | Although the DC-based immunotherapy of cancer has been promising in animal models, several questions need to be addressed in depth in humans: the generation of various types of dendritic cells, the analysis of their potential and the immunomonitoring of cancer patients. In our laboratory, our efforts have been focused on (i) the study of the cytotoxic activity of dendritic cells; (ii) the generation of a novel population of human dendritic cells from monocytes cultured in IL-3 and IFN-β; (iii) the optimisation of the immunostimulatory properties of DC using Fas-ligand surexpression or adjuvants promoting DC/γ-δ T cell interaction. © 2002 Éditions scientifiques et médicales Elsevier SAS. All rights reserved. |
