Titre :
  • Predicting the three-dimensional structure of human P-glycoprotein in absence of ATP by computational techniques embodying crosslinking data: insight into the mechanism of ligand migration and binding sites.
Auteur : Vandevuer, Stéphane ; Van Bambeke, Françoise ; Tulkens, Paul M. ; Prévost, Martine
Informations sur la publication : Proteins, 63, 3, (page 466-478)
Statut de publication : Publié, 2006-05
Sujet CREF : Chimie
Mots-clés : ABC transporters
Computer-assisted molecular modeling
Drug transport
Membrane proteins
Multidrug resistance
P-gp
Mots-clés MeSH : Adenosine Triphosphate -- chemistry
Adenosine Triphosphate -- genetics
Amino Acid Sequence
Binding Sites
Computational Biology -- methods
Cross-Linking Reagents -- chemistry
Escherichia coli Proteins -- chemistry
Escherichia coli Proteins -- genetics
Forecasting
Humans
Image Processing, Computer-Assisted -- methods
Ligands
Models, Structural
Molecular Sequence Data
P-Glycoprotein -- chemistry
P-Glycoprotein -- genetics
P-Glycoprotein -- metabolism
Protein Binding
Protein Structure, Tertiary
Note : Journal Article
Research Support, Non-U.S. Gov't
SCOPUS: ar.j
FLWIN
Langue :
  • Anglais
Identificateurs : urn:issn:0887-3585 
info:doi/10.1002/prot.20892
info:pmid/16463278