par Madani, Afarine ;Christophe, Catherine ;Ferster, Alina ;Dan, Bernard
Référence Pediatric radiology, 30, 1, page (30-32)
Publication Publié, 2000-01
Référence Pediatric radiology, 30, 1, page (30-32)
Publication Publié, 2000-01
Article révisé par les pairs
Résumé : | BACKGROUND: A 10-year-old boy with a history of acute lymphoblastic leukaemia (ALL), but without previous evidence of central nervous system involvement, presented with seizures 3 years after complete remission. MATERIALS AND METHODS: MRI showed bilateral enlargement of the optic nerves despite normal ophthalmological examination. RESULTS: Only the third cerebrospinal fluid examination showed 2 % blasts without concomitant bone-marrow infiltration. Enlargement of the optic nerves was consistent with bilateral leukaemic peri-optic nerve infiltration. The appearances returned to normal after chemotherapy. CONCLUSION: The optic nerves are a potential site of relapse in patients with systemic and meningeal ALL, even in the absence of ophthalmological signs. |