Titre:
  • The novel diazoxide analog 3-isopropylamino-7-methoxy-4H-1,2,4-benzothiadiazine 1,1-dioxide is a selective Kir6.2/SUR1 channel opener.
Auteur:Dabrowski, Michael; Ashcroft, Frances M; Ashfield, Rebecca; Lebrun, Philippe; Pirotte, Bernard; Egelbjerg, J; Hansen, John Bondo; Wahl, Philip
Informations sur la publication:Diabetes, 51, 6, page (1896-1906)
Statut de publication:Publié, 2002-06
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Adenosine Triphosphate -- analogs & derivatives
Adenosine Triphosphate -- pharmacology
Animals
Benzothiadiazines
Binding Sites
Cell Line
Cell Membrane -- metabolism
Diazoxide -- analogs & derivatives
Diazoxide -- metabolism
Diazoxide -- pharmacology
Electric Conductivity
Gene Expression
Glyburide -- metabolism
Hypoglycemic Agents -- metabolism
Ion Channel Gating -- drug effects
Mice
Mutagenesis
Oocytes -- metabolism
Potassium Channels, Inwardly Rectifying -- drug effects
Potassium Channels, Inwardly Rectifying -- genetics
Rats
Recombinant Fusion Proteins
Transfection
Tritium
Xenopus laevis
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0012-1797
info:pmid/12031979