Article révisé par les pairs
Titre :
  • New R/S-3,4-dihydro-2,2-dimethyl-2H-1-benzopyrans as K(ATP) channel openers: modulation of the 4-position.
Auteur : Florence, Xavier ; Sebille, Sophie ; de Tullio, Pascal ; Lebrun, Philippe ; Pirotte, Bernard
Informations sur la publication : Bioorganic & medicinal chemistry, 17, 22, (page 7723-7731)
Statut de publication : Publié, 2009-11
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés : Benzopyran derivatives
Cromakalim analogues
KATP channels
Potassium channel openers
Mots-clés MeSH : Adenosine Triphosphate -- metabolism
Animals
Benzopyrans -- chemical synthesis
Benzopyrans -- chemistry
Benzopyrans -- pharmacology
Cromakalim -- chemistry
Cromakalim -- pharmacology
Diazoxide -- chemistry
Diazoxide -- pharmacology
Islets of Langerhans -- drug effects
Islets of Langerhans -- metabolism
Muscle, Smooth, Vascular -- drug effects
Muscle, Smooth, Vascular -- metabolism
Pinacidil -- chemistry
Pinacidil -- pharmacology
Potassium Channels -- agonists
Potassium Channels -- metabolism
Rats
Rats, Wistar
Stereoisomerism
Structure-Activity Relationship
Vasodilator Agents -- chemical synthesis
Vasodilator Agents -- chemistry
Vasodilator Agents -- pharmacology
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0968-0896 
info:doi/10.1016/j.bmc.2009.09.041
info:pii/S0968-0896(09)00893-1
info:pmid/19822435