Titre :
  • Three-dimensional quantitative structure-activity relationships of ATP-sensitive potassium (KATP) channel openers belonging to the 3-alkylamino-4H-1,2,4-benzo- and 3-alkylamino-4H-1,2,4-pyridothiadiazine 1,1-dioxide families.
Auteur : de Tullio, Pascal ; Dupont, Léon ; Francotte, Pierre ; Counerotte, Stéphane ; Lebrun, Philippe ; Pirotte, Bernard
Informations sur la publication : Journal of medicinal chemistry, 49, 23, (page 6779-6788)
Statut de publication : Publié, 2006-11
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Adenosine Triphosphate -- physiology
Animals
Aorta -- drug effects
Aorta -- physiology
Cyclic S-Oxides -- chemistry
Cyclic S-Oxides -- pharmacology
Insulin -- secretion
Ion Channel Gating
Islets of Langerhans -- drug effects
Islets of Langerhans -- secretion
Models, Molecular
Muscle Contraction -- drug effects
Muscle, Smooth, Vascular -- drug effects
Muscle, Smooth, Vascular -- physiology
Potassium Channels -- chemistry
Pyridines -- chemistry
Pyridines -- pharmacology
Quantitative Structure-Activity Relationship
Rats
Thiadiazines -- chemistry
Thiadiazines -- pharmacology
Note : In Vitro
Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0022-2623 
info:doi/10.1021/jm060534w
info:pmid/17154508