Titre :
  • 2-alkyl-3-Alkylamino-2H-Benzo- and pyridothiadiazine 1,1-dioxides: from K+ATP channel openers to Ca++ channel blockers?
Auteur : Ouedraogo, Raogo ; Becker, Bénédicte ; Boverie, Stéphane ; Somers, Fabian ; Antoine, Marie-Hélène ; Pirotte, Bernard ; Lebrun, Philippe ; de Tullio, Pascal
Informations sur la publication : Biological chemistry, 383, 11, (page 1759-1768)
Statut de publication : Publié, 2002-11
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés : BPDZ 44
BPDZ 73
Inhibition of insulin release
Potassium channel openers
Vasorelaxant activity
Mots-clés MeSH : ATP-Binding Cassette Transporters
Alkanes -- chemical synthesis
Alkanes -- pharmacology
Animals
Aorta, Thoracic -- drug effects
Calcium Channel Blockers -- chemical synthesis
Calcium Channel Blockers -- pharmacology
Diazoxide -- chemical synthesis
Diazoxide -- pharmacology
Indicators and Reagents
Insulin -- metabolism
Islets of Langerhans -- drug effects
Islets of Langerhans -- metabolism
Muscle Contraction -- drug effects
Muscle, Smooth, Vascular -- drug effects
Potassium Channels -- agonists
Potassium Channels, Inwardly Rectifying
Rats
Rats, Wistar
Structure-Activity Relationship
Thiadiazines -- chemical synthesis
Thiadiazines -- pharmacology
Note : In Vitro
Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:1431-6730 
info:doi/10.1515/BC.2002.197
info:pmid/12530541