Titre :
  • Two new pimelic diphenylamide HDAC inhibitors induce sustained frataxin upregulation in cells from Friedreich's ataxia patients and in a mouse model.
Auteur : Rai, Myriam ; Soragni, Elisabetta ; Chou, C James ; Barnes, Glenn ; Jones, Steve ; Rusche, James R ; Gottesfeld, Joel M ; Pandolfo, Massimo
Informations sur la publication : PloS one, 5, 1, (page e8825)
Statut de publication : Publié, 2010
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Animals
Base Sequence
DNA Primers
Disease Models, Animal
Friedreich Ataxia -- genetics
Histone Deacetylase Inhibitors -- pharmacology
Humans
Iron-Binding Proteins -- genetics
Mice
Models, Animal
Pimelic Acids -- pharmacology
Polymerase Chain Reaction
Up-Regulation -- drug effects
Note : Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
SCOPUS: ar.j
Langue :
  • Anglais
Identificateurs : urn:issn:1932-6203 
info:doi/10.1371/journal.pone.0008825
info:pmid/20098685
info:pmcid/PMC2809102