Titre :
  • Controlled delivery of glial cell line-derived neurotrophic factor by a single tetracycline-inducible AAV vector.
Auteur : Chtarto, Abdelwahed ; Yang, Xin ; Bockstael, Olivier ; Melas, Catherine ; Blum, David ; Lehtonen, Enni ; Abeloos, Laurence ; Jaspar, J-M ; Levivier, Marc ; Brotchi, Jacques ; Velu, Thierry ; Tenenbaum, Liliane
Informations sur la publication : Experimental neurology, 204, 1, (page 387-399)
Statut de publication : Publié, 2007-03
Sujet CREF : Sciences bio-médicales et agricoles
Neurologie
Mots-clés : Adeno-associated virus
Downregulation
Glial cell line-derived neurotrophic factor
Parkinson
Serotype 1
Striatum
Tetracycline-inducible
Tyrosine hydroxylase
Mots-clés MeSH : Animals
Brain -- metabolism
Cell Line, Tumor
Corpus Striatum -- metabolism
DNA, Complementary -- metabolism
Dependovirus -- genetics
Dependovirus -- metabolism
Dose-Response Relationship, Drug
Down-Regulation
Doxycycline -- administration & dosage
Doxycycline -- pharmacology
Enzyme-Linked Immunosorbent Assay
Female
Gene Expression
Gene Transfer Techniques
Genetic Vectors -- drug effects
Glial Cell Line-Derived Neurotrophic Factor -- genetics
Green Fluorescent Proteins -- genetics
Humans
Immunohistochemistry
Injections
Rats
Rats, Sprague-Dawley
Tetracyclines -- pharmacology
Time Factors
Transduction, Genetic
Transgenes
Tyrosine 3-Monooxygenase -- metabolism
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0014-4886 
info:doi/10.1016/j.expneurol.2006.11.014
info:pii/S0014-4886(06)00630-3
info:pmid/17223106