Titre :
  • Enhanced signaling downstream of ribonucleic Acid-activated protein kinase-like endoplasmic reticulum kinase potentiates lipotoxic endoplasmic reticulum stress in human islets.
Auteur : Ladrière, Laurence ; Igoillo Esteve, Mariana ; Andrade Da Cunha, Daniel ; Brion, Jean Pierre ; Bugliani, Marco ; Marchetti, Piero ; Eizirik, Decio L. ; Cnop, Miriam
Informations sur la publication : The Journal of clinical endocrinology and metabolism, 95, 3, (page 1442-1449)
Statut de publication : Publié, 2010
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Analysis of Variance
Animals
Apoptosis -- drug effects
CCAAT-Enhancer-Binding Proteins -- metabolism
Cell Line
Cells, Cultured
Cinnamates -- pharmacology
Endoplasmic Reticulum -- drug effects
Endoplasmic Reticulum -- metabolism
Eukaryotic Initiation Factor-2 -- metabolism
Fluorescent Antibody Technique
Humans
Insulin-Secreting Cells -- cytology
Insulin-Secreting Cells -- drug effects
Insulin-Secreting Cells -- metabolism
Islets of Langerhans -- drug effects
Islets of Langerhans -- metabolism
Microscopy, Electron
Mitochondria -- drug effects
Mitochondria -- metabolism
Oleic Acid -- pharmacology
Palmitic Acid -- pharmacology
Phosphorylation
Rats
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction -- drug effects
Signal Transduction -- physiology
Thiourea -- analogs & derivatives
Thiourea -- pharmacology
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0021-972X 
info:doi/10.1210/jc.2009-2322
info:pii/jc.2009-2322
info:pmid/20080856