Titre :
  • In vivo retargeting of T cell effector function by recombinant bispecific single chain Fv (anti-CD3 x anti-idiotype) induces long-term survival in the murine BCL1 lymphoma model.
Auteur : De Jonge, Joost Kiewiet ; Heirman, Carlo ; de Veerman, Marijke ; Van Meirvenne, Sonja ; Moser, Muriel ; Leo, Oberdan ; Thielemans, Kris
Informations sur la publication : The Journal of immunology, 161, 3, (page 1454-1461)
Statut de publication : Publié, 1998-08
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Animals
Antibodies, Anti-Idiotypic -- biosynthesis
Antibodies, Anti-Idiotypic -- genetics
Antibodies, Anti-Idiotypic -- therapeutic use
Antibodies, Bispecific -- biosynthesis
Antibodies, Bispecific -- genetics
Antibodies, Bispecific -- therapeutic use
Antigens, CD3 -- immunology
Disease Models, Animal
Disease-Free Survival
Enterotoxins -- administration & dosage
Female
Genetic Vectors -- administration & dosage
Genetic Vectors -- immunology
Immunoglobulin Fragments -- biosynthesis
Immunoglobulin Fragments -- genetics
Immunoglobulin Fragments -- therapeutic use
Immunoglobulin Variable Region -- biosynthesis
Immunoglobulin Variable Region -- genetics
Immunoglobulin Variable Region -- therapeutic use
Injections, Intravenous
Lymphocyte Activation
Lymphoma, B-Cell -- immunology
Lymphoma, B-Cell -- mortality
Lymphoma, B-Cell -- therapy
Mice
Mice, Inbred BALB C
Neoplasm Transplantation
Recombinant Proteins -- biosynthesis
Recombinant Proteins -- immunology
Recombinant Proteins -- therapeutic use
T-Lymphocytes -- immunology
Tumor Cells, Cultured
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0022-1767 
info:pmid/9686611