Titre :
  • A phase 1-2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir.
Auteur : Shand, N. ; Weber, F ; Mariani, Luigi ; Bernstein, Mark ; Gianella-Borradori, Athos ; Long, Z. ; Sorensen, AG ; Barbier, Nicolas Serge ; GLI328 European-canadian study group
Informations sur la publication : Human gene therapy, 10, 14, (page 2325-2335)
Statut de publication : Publié, 1999-09
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Adult
Aged
Antiviral Agents -- therapeutic use
Brain -- pathology
Brain -- surgery
Brain Neoplasms -- surgery
Brain Neoplasms -- therapy
Combined Modality Therapy
Female
Ganciclovir -- therapeutic use
Gene Therapy
Glioblastoma -- surgery
Glioblastoma -- therapy
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Neoplasm Recurrence, Local
Simplexvirus -- enzymology
Simplexvirus -- genetics
Survival Analysis
Thymidine Kinase -- genetics
Note : Clinical Trial
Clinical Trial, Phase I
Clinical Trial, Phase II
Journal Article
Multicenter Study
Langue :
  • Anglais
Identificateurs : urn:issn:1043-0342 
info:doi/10.1089/10430349950016979
info:pmid/10515452