par Biver, Françoise 
;Goldman, Serge ;François, Anne ;De La Porte, C;Luxen, André ;Gribomont, Bruno ;Lotstra, Françoise
Référence Journal of neurology, neurosurgery and psychiatry, 58, 4, page (502-505)
Publication Publié, 1995-04
;Goldman, Serge ;François, Anne ;De La Porte, C;Luxen, André ;Gribomont, Bruno ;Lotstra, Françoise Référence Journal of neurology, neurosurgery and psychiatry, 58, 4, page (502-505)
Publication Publié, 1995-04
Article révisé par les pairs
| Résumé : | Brain glucose metabolism was investigated with PET and [18F]fluorodeoxyglucose, before and after a bifrontal stereotactic leukotomy in a 37 year old woman with refractory obsessive-compulsive disorder. A bilateral decrease in glucose metabolism was found in the orbital frontal cortex after psychosurgery. Glucose metabolism was decreased to a lesser degree in Brodmann's area 25, in the thalamus, and in the caudate nucleus. Clinical improvement in obsessive-compulsive disorder after stereotactic tractotomy seems to be associated with metabolic changes in the brain, in particular, in the orbital part of the frontal lobe. |
