Titre :
  • Exposure of pancreatic islets to different alkylating agents decreases mitochondrial DNA content but only streptozotocin induces long-lasting functional impairment of B-cells.
Auteur : Eizirik, Decio L. ; Sandler, S ; Ahnström, G ; Welsh, M
Informations sur la publication : Biochemical pharmacology, 42, 12, (page 2275-2282)
Statut de publication : Publié, 1991
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Adenine -- analogs & derivatives
Adenine -- analysis
Alkylating Agents -- pharmacology
Animals
Cytochrome b Group -- genetics
DNA -- metabolism
Dose-Response Relationship, Drug
Glucagon -- genetics
Glucose -- pharmacology
Guanine -- analogs & derivatives
Guanine -- analysis
Immunoblotting
Insulin -- analysis
Insulin -- genetics
Islets of Langerhans -- drug effects
Islets of Langerhans -- metabolism
Islets of Langerhans -- physiology
Male
Methyl Methanesulfonate -- pharmacology
Methylnitrosourea -- pharmacology
Mice
Mitochondria -- drug effects
RNA, Messenger -- analysis
Streptozocin -- pharmacology
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0006-2952 
info:pmid/1837218