Titre :
  • Interleukin-1 beta induces an early decrease in insulin release, (pro)insulin biosynthesis and insulin mRNA in mouse pancreatic islets by a mechanism dependent on gene transcription and protein synthesis.
Auteur : Eizirik, Decio L.
Informations sur la publication : Autoimmunity, 10, 2, (page 107-113)
Statut de publication : Publié, 1991
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Animals
DNA Replication
Dactinomycin -- pharmacology
Enzyme Induction -- drug effects
Glucose -- metabolism
Insulin -- biosynthesis
Insulin -- genetics
Insulin -- secretion
Interleukin-1 -- pharmacology
Islets of Langerhans -- drug effects
Islets of Langerhans -- metabolism
Male
Mice
Organ Culture Techniques
Proinsulin -- biosynthesis
Protein Biosynthesis
RNA, Messenger -- biosynthesis
Recombinant Proteins -- pharmacology
Stimulation, Chemical
Transcription, Genetic -- drug effects
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0891-6934 
info:pmid/1782324