Titre:
  • Cytotoxic T cells deficient in both functional fas ligand and perforin show residual cytolytic activity yet lose their capacity to induce lethal acute graft-versus-host disease.
Auteur:Braun, Michel Y; Lowin, B; French, L; Acha-Orbea, H; Tschopp, J
Informations sur la publication:The Journal of experimental medicine, 183, 2, page (657-661)
Statut de publication:Publié, 1996-02
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Animals
Base Sequence
Cytotoxicity, Immunologic -- genetics
Fas Ligand Protein
Female
Flow Cytometry
Graft vs Host Disease -- etiology
Graft vs Host Disease -- immunology
Graft vs Host Disease -- mortality
Graft vs Host Disease -- pathology
Membrane Glycoproteins -- deficiency
Membrane Glycoproteins -- genetics
Mice
Mice, Inbred C57BL
Mice, Knockout
Molecular Sequence Data
Perforin
Pore Forming Cytotoxic Proteins
Spleen -- cytology
Spleen -- immunology
Survival Analysis
T-Lymphocytes, Cytotoxic -- immunology
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0022-1007
info:pmid/8627178
PMC2192472