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Pharmacokinetic and phase I studies of brequinar (DUP 785; NSC 368390) in combination with cisplatin in patients with advanced malignancies.

par Burris, Howard A;Raymond, E;Awada, Ahmad ;Kuhn, Josée ;O'Rourke, T J;Brentzel, J;Lynch, W;King, Susanne;Brown, T D;Von Hoff, D D
Référence Investigational new drugs, 16, 1, page (19-27)
Publication Publié, 1998

Article révisé par les pairs

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Titre:	Pharmacokinetic and phase I studies of brequinar (DUP 785; NSC 368390) in combination with cisplatin in patients with advanced malignancies.
Auteur:	Burris, Howard A; Raymond, E; Awada, Ahmad; Kuhn, Josée; O'Rourke, T J; Brentzel, J; Lynch, W; King, Susanne; Brown, T D; Von Hoff, D D
Informations sur la publication:	Investigational new drugs, 16, 1, page (19-27)
Statut de publication:	Publié, 1998
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Adolescent
	Adult
	Aged
	Antineoplastic Combined Chemotherapy Protocols -- adverse effects
	Antineoplastic Combined Chemotherapy Protocols -- pharmacokinetics
	Antineoplastic Combined Chemotherapy Protocols -- therapeutic use
	Biphenyl Compounds -- administration & dosage
	Biphenyl Compounds -- adverse effects
	Biphenyl Compounds -- pharmacokinetics
	Cisplatin -- administration & dosage
	Cisplatin -- adverse effects
	Cisplatin -- pharmacokinetics
	Female
	Humans
	Male
	Middle Aged
	Neoplasms -- drug therapy
	Neoplasms -- metabolism
	Treatment Outcome
Note générale:	Clinical Trial
	Clinical Trial, Phase I
	Journal Article
Langue:	Anglais
Identificateurs:	urn:issn:0167-6997
	info:pmid/9740540