Titre :
  • Suppressor of cytokine signalling-3 expression inhibits cytokine-mediated destruction of primary mouse and rat pancreatic islets and delays allograft rejection.
Auteur : Rønn, S G ; Börjesson, A ; Bruun, C ; Heding, P E ; Frobøse, H ; Mandrup-Poulsen, T. ; Karlsen, A E ; Rasschaert, Joanne ; Sandler, S ; Billestrup, N
Informations sur la publication : Diabetologia, 51, 10, (page 1873-1882)
Statut de publication : Publié, 2008-10
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés : Apoptosis
Autoimmunity
Diabetes
IFNγ
IL-1
Inflammation
Signalling
SOCS
Suppressor of cytokine signalling
Mots-clés MeSH : Alloxan
Animals
Animals, Newborn
Apoptosis -- genetics
Apoptosis -- physiology
Blotting, Western
Cytokines -- metabolism
Diabetes Mellitus, Experimental -- chemically induced
Diabetes Mellitus, Experimental -- physiopathology
Graft Survival -- genetics
Graft Survival -- physiology
Humans
In Situ Nick-End Labeling
Islets of Langerhans -- cytology
Islets of Langerhans -- metabolism
Islets of Langerhans Transplantation -- methods
Mice
Mice, Inbred C57BL
Mice, Inbred NOD
Mice, Transgenic
Rats
Reverse Transcriptase Polymerase Chain Reaction
Suppressor of Cytokine Signaling Proteins -- genetics
Suppressor of Cytokine Signaling Proteins -- metabolism
Suppressor of Cytokine Signaling Proteins -- physiology
Transplantation, Homologous
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0012-186X 
info:doi/10.1007/s00125-008-1090-0
info:pmid/18648765