Titre :
  • Endocannabinoid and serotonergic systems are needed for acetaminophen-induced analgesia.
Auteur : Mallet, Christophe ; Daulhac, Laurence ; Bonnefont, Jérôme ; Ledent, Catherine ; Etienne, Monique ; Chapuy, Eric ; Libert, Frédérick ; Eschalier, Alain
Informations sur la publication : Pain, 139, 1, (page 190-200)
Statut de publication : Publié, 2008-09
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés : Acetaminophen
Endocannabinoids
Fatty acid amide hydrolase
Nociception
Serotonin
Mots-clés MeSH : Acetaminophen -- pharmacology
Acetaminophen -- therapeutic use
Analgesia -- methods
Animals
Dose-Response Relationship, Drug
Endocannabinoids -- antagonists & inhibitors
Endocannabinoids -- physiology
Male
Mice
Mice, Knockout
Pain -- drug therapy
Pain -- metabolism
Pain Measurement -- drug effects
Pain Measurement -- methods
Piperidines -- pharmacology
Pyrazoles -- pharmacology
Rats
Rats, Sprague-Dawley
Receptor, Cannabinoid, CB1 -- antagonists & inhibitors
Receptor, Cannabinoid, CB1 -- physiology
Receptors, Serotonin -- physiology
Serotonin -- physiology
Serotonin -- secretion
Note : Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0304-3959 
info:doi/10.1016/j.pain.2008.03.030
info:pii/S0304-3959(08)00171-1
info:pmid/18485596