Article révisé par les pairs
Titre:
  • A2A adenosine receptor deficiency leads to impaired tracheal relaxation via NADPH oxidase pathway in allergic mice.
Auteur:Nadeem, A; Ponnoth, Dovenia S; Ansari, H R; Batchelor, T P; Dey, R D; Ledent, Catherine; Mustafa, S Jamal
Informations sur la publication:The Journal of pharmacology and experimental therapeutics, 330, 1, page (99-108)
Statut de publication:Publié, 2009-07
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Adenosine -- analogs & derivatives
Adenosine -- pharmacology
Animals
Asthma -- enzymology
Asthma -- metabolism
Asthma -- physiopathology
Disease Models, Animal
Female
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Muscle Relaxation -- drug effects
Muscle Relaxation -- genetics
Muscle Relaxation -- physiology
Muscle, Smooth -- drug effects
Muscle, Smooth -- enzymology
Muscle, Smooth -- metabolism
Muscle, Smooth -- physiopathology
NADPH Oxidase -- physiology
Phenethylamines -- pharmacology
Reactive Oxygen Species -- metabolism
Receptor, Adenosine A2A -- agonists
Receptor, Adenosine A2A -- deficiency
Receptor, Adenosine A2A -- genetics
Signal Transduction -- drug effects
Signal Transduction -- genetics
Signal Transduction -- physiology
Trachea -- enzymology
Trachea -- metabolism
Trachea -- physiopathology
Note générale:Comparative Study
In Vitro
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0022-3565
info:doi/10.1124/jpet.109.151613
info:pii/jpet.109.151613
info:scp/67649873066
info:pmid/19395654