Titre :
  • Safety, pharmacokinetics, and preliminary antitumor activity of sorafenib: a review of four phase I trials in patients with advanced refractory solid tumors.
Auteur : Strumberg, Dirk ; Clark, Jeffrey W ; Awada, Ahmad ; Moore, Malcolm J ; Richly, Heike ; Hendlisz, Alain ; Hirte, Hal W ; Eder, Joseph P ; Lenz, Heinz-Josef ; Schwartz, Brian
Informations sur la publication : The oncologist, 12, 4, (page 426-437)
Statut de publication : Publié, 2007-04
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés : BAY 43-9006
Phase I clinical trials
Review
Sorafenib
Mots-clés MeSH : Antineoplastic Agents -- administration & dosage
Antineoplastic Agents -- pharmacokinetics
Antineoplastic Agents -- therapeutic use
Benzenesulfonates -- administration & dosage
Benzenesulfonates -- pharmacokinetics
Benzenesulfonates -- therapeutic use
Clinical Trials, Phase I as Topic
Humans
Neoplasm Metastasis
Neoplasms -- drug therapy
Neoplasms -- pathology
Protein Kinase Inhibitors -- administration & dosage
Protein Kinase Inhibitors -- pharmacokinetics
Protein Kinase Inhibitors -- therapeutic use
Pyridines -- administration & dosage
Pyridines -- pharmacokinetics
Pyridines -- therapeutic use
raf Kinases -- antagonists & inhibitors
Note : Journal Article
Review
Langue :
  • Anglais
Identificateurs : urn:issn:1083-7159 
info:doi/10.1634/theoncologist.12-4-426
info:pii/12/4/426
info:pmid/17470685