Titre :
  • Phase I dose escalation study of weekly ixabepilone, an epothilone analog, in patients with advanced solid tumors who have failed standard therapy.
Auteur : Awada, Ahmad ; Piccart-Gebhart, Martine ; Jones, Suzanne F ; Peck, Ronald A ; Gil, Thierry ; Lebwohl, David ; Wu, Chi-Yuan ; Burris, Howard A
Informations sur la publication : Cancer chemotherapy and pharmacology, 63, 3, (page 417-425)
Statut de publication : Publié, 2009-02
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés : Dose-finding
Ixabepilone
Solid tumors
Weekly schedule
Mots-clés MeSH : Aged
Antineoplastic Agents -- administration & dosage
Antineoplastic Agents -- adverse effects
Antineoplastic Agents -- therapeutic use
Cohort Studies
Epothilones -- administration & dosage
Epothilones -- adverse effects
Epothilones -- pharmacokinetics
Epothilones -- therapeutic use
Female
Humans
Male
Maximum Tolerated Dose
Middle Aged
Neoplasms -- drug therapy
Note : Clinical Trial, Phase I
Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0344-5704 
info:doi/10.1007/s00280-008-0751-5
info:pmid/18446338