Titre :
  • A lack of thyroid hormones rather than excess thyrotropin causes abnormal skeletal development in hypothyroidism.
Auteur : Bassett, J H Duncan ; Williams, Allan J ; Murphy, Elaine ; Boyde, Alan ; Howell, Peter ; Swinhoe, Rowan ; Archanco, Marta ; Flamant, Frédéric ; Samarut, Jacques ; Costagliola, Sabine ; Vassart, Gilbert ; Weiss, R E ; Refetoff, Samuel ; Williams, Graham
Informations sur la publication : Molecular endocrinology, 22, 2, (page 501-512)
Statut de publication : Publié, 2008-02
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Animals
Blotting, Western
Bone Development -- drug effects
Bone Development -- genetics
Bone Development -- physiology
Bone Remodeling -- drug effects
Bone Remodeling -- genetics
Bone Remodeling -- physiology
Bone and Bones -- abnormalities
Bone and Bones -- metabolism
Calcification, Physiologic -- drug effects
Calcification, Physiologic -- genetics
Calcification, Physiologic -- physiology
Cell Differentiation -- drug effects
Cell Differentiation -- genetics
Cell Differentiation -- physiology
Cells, Cultured
Cyclic AMP -- metabolism
Hypothyroidism -- blood
Hypothyroidism -- genetics
Hypothyroidism -- pathology
In Situ Hybridization
Mice
Mice, Knockout
Osteoblasts -- cytology
Osteoblasts -- drug effects
Osteoblasts -- metabolism
Osteoclasts -- cytology
Osteoclasts -- drug effects
Osteoclasts -- metabolism
Osteogenesis -- drug effects
Osteogenesis -- physiology
Paired Box Transcription Factors -- genetics
Paired Box Transcription Factors -- metabolism
Paired Box Transcription Factors -- physiology
Reverse Transcriptase Polymerase Chain Reaction
Thyroid Gland -- metabolism
Thyroid Hormones -- blood
Thyroid Hormones -- pharmacology
Thyrotropin -- blood
Note : Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0888-8809 
info:doi/10.1210/me.2007-0221
info:pii/me.2007-0221
info:pmid/17932107
info:pmcid/PMC2234586