Titre:
  • Valproate activates bovine leukemia virus gene expression, triggers apoptosis, and induces leukemia/lymphoma regression in vivo.
Auteur:Achachi, Amine; Florins, Arnaud; Gillet, Nicolas; Debacq, Christophe; Urbain, Patrice; Foutsop, Germain Manfouo; Vandermeers, Fabian; Jasik, Agnieszka; Reichert, M; Kerkhofs, Pierre; Lagneaux, Laurence; Burny, Arsène; Kettmann, Richard; Willems, Lucas
Informations sur la publication:Proceedings of the National Academy of Sciences of the United States of America, 102, 29, page (10309-10314)
Statut de publication:Publié, 2005-07
Sujet CREF:Sciences bio-médicales et agricoles
Mots-clés:Gene activation therapy
Histone deacetylase
Immune response
MeSH keywords:Animals
Apoptosis -- drug effects
B-Lymphocytes -- metabolism
Enzyme-Linked Immunosorbent Assay
Flow Cytometry
Gene Expression Regulation, Viral -- drug effects
Hela Cells
Histone Deacetylase Inhibitors
Humans
Leukemia Virus, Bovine -- metabolism
Leukemia, Lymphoid -- therapy
Leukocytes, Mononuclear -- metabolism
Luciferases
Lymphocyte Count
Proviruses -- metabolism
Remission Induction
Sheep
Valproic Acid -- pharmacology
Valproic Acid -- therapeutic use
Note générale:Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:0027-8424
info:doi/10.1073/pnas.0504248102
info:pii/0504248102
info:scp/22544443905
info:pmid/16006517
PMC1177395