Article révisé par les pairs
Titre :
  • Conditional and specific NF-kappaB blockade protects pancreatic beta cells from diabetogenic agents.
Auteur : Eldor, R ; Yeffet, A ; Baum, K ; Doviner, V ; Amar, D ; Ben-Neriah, Y ; Christofori, G ; Peled, Amnon ; Carel, J C ; Boitard, C ; Klein, T ; Serup, P ; Eizirik, Decio L. ; Melloul, D
Informations sur la publication : Proceedings of the National Academy of Sciences of the United States of America, 103, 13, (page 5072-5077)
Statut de publication : Publié, 2006
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés : Apoptosis
Cytokine
Diabetes transgenic mice
Insulin
Mots-clés MeSH : Active Transport, Cell Nucleus -- drug effects
Animals
Apoptosis -- drug effects
Cytokines
DNA -- metabolism
Diabetes Mellitus, Experimental -- chemically induced
Diabetes Mellitus, Experimental -- genetics
Diabetes Mellitus, Experimental -- metabolism
Diabetes Mellitus, Experimental -- pathology
Doxycycline -- pharmacology
Drug Resistance -- drug effects
Gene Expression Regulation, Enzymologic
I-kappa B Kinase -- genetics
I-kappa B Kinase -- metabolism
Interferon-gamma -- pharmacology
Interleukin-1 -- pharmacology
Islets of Langerhans -- drug effects
Islets of Langerhans -- metabolism
Islets of Langerhans -- pathology
Lymphocytes -- cytology
Mice
Mice, Transgenic
Mutation -- genetics
NF-kappa B -- antagonists & inhibitors
NF-kappa B -- metabolism
Protein Binding
Streptozocin -- pharmacology
Tissue Culture Techniques
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0027-8424 
info:doi/10.1073/pnas.0508166103
info:pii/0508166103
info:pmid/16551748
info:pmcid/PMC1458796