Titre :
  • Extracellular signal-regulated kinase is essential for interleukin-1-induced and nuclear factor kappaB-mediated gene expression in insulin-producing INS-1E cells.
Auteur : Larsen, L ; Størling, Joachim ; Darville, Martine ; Eizirik, Decio L. ; Bonny, Christophe ; Billestrup, N ; Mandrup-Poulsen, T.
Informations sur la publication : Diabetologia, 48, 12, (page 2582-2590)
Statut de publication : Publié, 2005
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés : IL-1β
Mitogen-activated protein kinases
Nitric oxide
Nuclear factor kappa B
Pancreatic beta cells
Type 1 diabetes
Mots-clés MeSH : Animals
Apoptosis -- genetics
Blotting, Western
Cell Line, Tumor
Extracellular Signal-Regulated MAP Kinases -- antagonists & inhibitors
Extracellular Signal-Regulated MAP Kinases -- physiology
Flavonoids -- pharmacology
Gene Expression -- drug effects
Gene Expression -- physiology
Humans
Imidazoles -- pharmacology
Insulin -- secretion
Insulin-Secreting Cells -- drug effects
Insulin-Secreting Cells -- physiology
Insulin-Secreting Cells -- secretion
Interleukin-1 -- pharmacology
Interleukin-1 -- physiology
MAP Kinase Kinase 4 -- antagonists & inhibitors
MAP Kinase Kinase 4 -- physiology
Mitogen-Activated Protein Kinase Kinases -- antagonists & inhibitors
Mitogen-Activated Protein Kinase Kinases -- physiology
NF-kappa B -- physiology
Nitric Oxide Synthase Type II -- biosynthesis
Nitric Oxide Synthase Type II -- genetics
Phosphorylation
Pyridines -- pharmacology
Rats
Serine -- analysis
Synaptotagmin I -- chemistry
Synaptotagmin I -- physiology
p38 Mitogen-Activated Protein Kinases -- antagonists & inhibitors
p38 Mitogen-Activated Protein Kinases -- physiology
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0012-186X 
info:doi/10.1007/s00125-005-0039-9
info:pmid/16283237