Titre:
  • Interleukin-18 mRNA, but not interleukin-18 receptor mRNA, is constitutively expressed in islet beta-cells and up-regulated by interferon-gamma.
Auteur:Hong, T P; Andersen, N A; Nielsen, K; Karlsen, A E; Puren, AJ; Fantuzzi, G; Eizirik, Decio L.; Dinarello, C A; Mandrup-Poulsen, T.
Informations sur la publication:European cytokine network, 11, 2, page (193-205)
Statut de publication:Publié, 2000
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Animals
Base Sequence
Cell Line
DNA Primers -- genetics
DNA-Binding Proteins -- genetics
DNA-Binding Proteins -- metabolism
Diabetes Mellitus, Type 1 -- etiology
Diabetes Mellitus, Type 1 -- genetics
Diabetes Mellitus, Type 1 -- immunology
Gene Expression
Humans
Insulin -- secretion
Interferon Regulatory Factor-1
Interferon-gamma, Recombinant -- pharmacology
Interleukin-1 -- pharmacology
Interleukin-18 -- genetics
Interleukin-18 -- pharmacology
Interleukin-18 Receptor alpha Subunit
Islets of Langerhans -- drug effects
Islets of Langerhans -- immunology
Islets of Langerhans -- physiology
Mice
Mice, Knockout
Nitric Oxide -- biosynthesis
Phosphoproteins -- genetics
Phosphoproteins -- metabolism
RNA, Messenger -- genetics
RNA, Messenger -- metabolism
Rats
Rats, Inbred WF
Receptors, Interleukin -- genetics
Receptors, Interleukin-18
Tumor Necrosis Factor-alpha -- pharmacology
Up-Regulation -- drug effects
Note générale:In Vitro
Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:1148-5493
info:pmid/10903798