Titre:
  • LGR5 deficiency deregulates Wnt signaling and leads to precocious Paneth cell differentiation in the fetal intestine.
Auteur:Garcia, Marie-Isabelle; Ghiani, Mariangela; Lefort, Anne; Libert, Frédérick; Strollo, Sandra; Vassart, Gilbert
Informations sur la publication:Developmental biology, 331, 1, page (58-67)
Statut de publication:Publié, 2009-07
Sujet CREF:Sciences bio-médicales et agricoles
Mots-clés:Fetal intestine
GPCR
GPR49
LGR5
Orphan receptor
Paneth cells
Stem cells
Wnt signaling
MeSH keywords:Animals
Base Sequence
Bromodeoxyuridine
Cell Differentiation
Cell Division
Cell Movement
DNA Primers
Embryonic Development -- genetics
Female
Gene Expression
Gene Expression Regulation, Developmental
Ileum -- embryology
In Situ Hybridization
Intestine, Small -- cytology
Intestine, Small -- embryology
Mice
Mice, Inbred C57BL
Molecular Sequence Data
Oligonucleotide Array Sequence Analysis
Paneth Cells -- cytology
Pregnancy
Receptors, G-Protein-Coupled -- deficiency
Receptors, G-Protein-Coupled -- genetics
Reverse Transcriptase Polymerase Chain Reaction
Transcription, Genetic
Wnt Proteins -- physiology
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0012-1606
info:doi/10.1016/j.ydbio.2009.04.020
info:pii/S0012-1606(09)00266-8
info:scp/67349197237
info:pmid/19394326