Titre:
  • The TXP motif in the second transmembrane helix of CCR5. A structural determinant of chemokine-induced activation.
Auteur:Govaerts, Cédric; Blanpain, Cédric; Deupi, Xavier; Ballet, Sébastien; Ballesteros, Juan Antonio; Wodak, Shoshana; Vassart, Gilbert; Pardo, Leonardo; Parmentier, Marc
Informations sur la publication:The Journal of biological chemistry, 276, 16, page (13217-13225)
Statut de publication:Publié, 2001-04
Sujet CREF:Sciences bio-médicales et agricoles
Biochimie
Biologie
Biologie cellulaire
Biologie moléculaire
Biophysique
Sciences biomédicales
MeSH keywords:Amino Acid Sequence
Amino Acid Substitution
Animals
Binding Sites
CHO Cells
Cattle
Chemokine CCL4
Chemokine CCL5 -- pharmacokinetics
Chemokine CCL5 -- pharmacology
Chemokine CCL8
Chemokines -- pharmacology
Cricetinae
GTP-Binding Proteins -- metabolism
Humans
Macrophage Inflammatory Proteins -- pharmacology
Mice
Models, Molecular
Molecular Sequence Data
Monocyte Chemoattractant Proteins -- pharmacology
Mutagenesis, Site-Directed
Protein Structure, Secondary
Receptors, CCR5 -- chemistry
Receptors, CCR5 -- drug effects
Receptors, CCR5 -- physiology
Receptors, Chemokine -- chemistry
Receptors, HIV -- chemistry
Receptors, HIV -- drug effects
Receptors, HIV -- physiology
Recombinant Proteins -- chemistry
Recombinant Proteins -- drug effects
Recombinant Proteins -- metabolism
Rhodopsin -- chemistry
Sequence Alignment
Sequence Homology, Amino Acid
Transfection
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0021-9258
info:doi/10.1074/jbc.M011670200
info:pii/M011670200
info:scp/0035918313
info:pmid/11278962