Titre :
  • Lysine 195 and aspartate 196 in the first extracellular loop of the VPAC1 receptor are essential for high affinity binding of agonists but not of antagonists.
Auteur : Langer, Ingrid ; Vertongen, Pascale ; Perret, Jason ; Waelbroeck, Magali ; Robberecht, Patrick
Informations sur la publication : Neuropharmacology, 44, 1, (page 125-131)
Statut de publication : Publié, 2003-01
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Adenylate Cyclase -- metabolism
Amino Acid Substitution
Aspartic Acid -- genetics
Binding, Competitive
CHO Cells
Cell Membrane -- metabolism
Lysine -- genetics
Mutagenesis, Site-Directed
Protein Structure, Secondary
Radioligand Assay
Receptors, Vasoactive Intestinal Peptide -- agonists
Receptors, Vasoactive Intestinal Peptide -- antagonists & inhibitors
Receptors, Vasoactive Intestinal Peptide -- metabolism
Receptors, Vasoactive Intestinal Polypeptide, Type I
Structure-Activity Relationship
Vasoactive Intestinal Peptide -- metabolism
Note : Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0028-3908