Titre :
  • Octreotide, a somatostatin analogue, mediates its antiproliferative action in pituitary tumor cells by altering phosphatidylinositol 3-kinase signaling and inducing Zac1 expression.
Auteur : Theodoropoulou, Marily ; Zhang, Jing ; Laupheimer, Sandra ; Paez-Pereda, Marcelo ; Erneux, Christophe ; Florio, Tullio ; Pagotto, Uberto ; Stalla, Günter K
Informations sur la publication : Cancer research, 66, 3, (page 1576-1582)
Statut de publication : Publié, 2006-02
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : 1-Phosphatidylinositol 3-Kinase -- antagonists & inhibitors
1-Phosphatidylinositol 3-Kinase -- metabolism
Animals
Cell Growth Processes -- drug effects
DNA-Binding Proteins -- antagonists & inhibitors
DNA-Binding Proteins -- biosynthesis
DNA-Binding Proteins -- genetics
Enzyme Activation -- drug effects
Gene Expression Regulation, Neoplastic -- drug effects
Genes, Tumor Suppressor
Glycogen Synthase Kinase 3 -- metabolism
Octreotide -- pharmacology
Pertussis Toxin -- pharmacology
Phosphorylation -- drug effects
Pituitary Neoplasms -- drug therapy
Pituitary Neoplasms -- genetics
Pituitary Neoplasms -- metabolism
Pituitary Neoplasms -- pathology
Protein Tyrosine Phosphatases -- antagonists & inhibitors
Protein Tyrosine Phosphatases -- metabolism
RNA, Small Interfering -- genetics
Rats
Signal Transduction -- drug effects
Vanadates -- pharmacology
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0008-5472 
info:doi/10.1158/0008-5472.CAN-05-1189
info:pii/66/3/1576
info:pmid/16452215