Titre:
  • Asn229 in the third helix of VPAC1 receptor is essential for receptor activation but not for receptor phosphorylation and internalization: comparison with Asn216 in VPAC2 receptor.
Auteur:Nachtergael, Ingrid; Gaspard, Nathalie; Langlet, Christelle; Robberecht, Patrick; Langer, Ingrid
Informations sur la publication:Cellular signalling, 18, 12, page (2121-2130)
Statut de publication:Publié, 2006-12
Sujet CREF:Sciences bio-médicales et agricoles
Mots-clés:G protein activation
Receptor internalization
Receptor phosphorylation
TM helix
VPAC1 receptor
VPAC2 receptor
MeSH keywords:Adenylate Cyclase -- metabolism
Amino Acid Sequence
Animals
Asparagine -- genetics
Asparagine -- metabolism
Binding, Competitive
Biological Transport -- physiology
CHO Cells
Calcium -- metabolism
Cell Membrane -- drug effects
Cell Membrane -- metabolism
Cricetinae
Cricetulus
Endocytosis -- physiology
Enzyme Activation -- drug effects
Kinetics
Molecular Sequence Data
Mutagenesis, Site-Directed
Mutation -- genetics
Phosphorylation
Receptors, Vasoactive Intestinal Peptide, Type II -- genetics
Receptors, Vasoactive Intestinal Peptide, Type II -- metabolism
Receptors, Vasoactive Intestinal Polypeptide, Type I -- genetics
Receptors, Vasoactive Intestinal Polypeptide, Type I -- metabolism
Sequence Homology, Amino Acid
Transfection
Vasoactive Intestinal Peptide -- analogs & derivatives
Vasoactive Intestinal Peptide -- metabolism
Vasoactive Intestinal Peptide -- pharmacology
Note générale:Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0898-6568
info:doi/10.1016/j.cellsig.2006.03.006
info:pii/S0898-6568(06)00072-6
info:scp/33750314184
info:pmid/16650965