Titre :
  • Insulin increase in MAP kinase phosphorylation is shifted to early time-points by overexpressing APS, while Akt phosphorylation is not influenced.
Auteur : Onnockx, SHEELA ; Xie, Jingwei ; Degraef, Chantal ; Erneux, Christophe ; Pirson, Isabelle
Informations sur la publication : Experimental cell research, 315, 15, (page 2479-2486)
Statut de publication : Publié, 2009-09
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés : Adaptor protein APS
Insulin
MAPK
PI 3-kinase
PKB
SHIP2
Mots-clés MeSH : 1-Phosphatidylinositol 3-Kinase -- antagonists & inhibitors
1-Phosphatidylinositol 3-Kinase -- genetics
1-Phosphatidylinositol 3-Kinase -- metabolism
Adaptor Proteins, Signal Transducing -- genetics
Adaptor Proteins, Signal Transducing -- metabolism
Animals
CHO Cells
Cell Membrane -- metabolism
Cricetinae
Cricetulus
Enzyme Activation
Inositol Phosphates -- metabolism
Insulin -- metabolism
Mitogen-Activated Protein Kinases -- metabolism
Mutagenesis, Site-Directed
Phosphorylation
Point Mutation
Proto-Oncogene Proteins c-akt -- metabolism
Signal Transduction -- physiology
src Homology Domains
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0014-4827 
info:doi/10.1016/j.yexcr.2009.06.006
info:pii/S0014-4827(09)00269-9
info:pmid/19527711