Titre :
  • New pyridinone derivatives as potent HIV-1 nonnucleoside reverse transcriptase inhibitors.
Auteur : Le Van, Kiet ; Cauvin, Christine ; De Walque, Stéphane ; Georges, Benoît ; Boland, Sandro ; Martinelli, Valérie ; Demonte, Dominique ; Durant, François ; Hevesi, László ; Van Lint, Carine
Informations sur la publication : Journal of medicinal chemistry, 52, 12, (page 3636-3643)
Statut de publication : Publié, 2009
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Anti-HIV Agents -- chemical synthesis
Anti-HIV Agents -- chemistry
Anti-HIV Agents -- pharmacology
Binding Sites
Cell Line
Cell Survival -- drug effects
Cell Transformation, Viral -- drug effects
Computer Simulation
Crystallography, X-Ray
HIV -- drug effects
HIV Reverse Transcriptase -- antagonists & inhibitors
Humans
Microbial Sensitivity Tests
Models, Chemical
Models, Molecular
Molecular Structure
Pyridones -- chemical synthesis
Pyridones -- chemistry
Pyridones -- pharmacology
Reverse Transcriptase Inhibitors -- chemical synthesis
Reverse Transcriptase Inhibitors -- chemistry
Reverse Transcriptase Inhibitors -- pharmacology
Stereoisomerism
Structure-Activity Relationship
Note : Journal Article
Research Support, Non-U.S. Gov't
SCOPUS: ar.j
Langue :
  • Anglais
Identificateurs : urn:issn:0022-2623 
info:doi/10.1021/jm801438e
info:pmid/19469474