par Liberale, Gabriel ;Van Laethem, Jean-Luc ;Gay, France ;Goldman, Serge ;Nagy, Nathalie ;Coppens, Emmanuel ;Gelin, Michel ;Nakadi, I.
Référence European journal of surgical oncology, 30, 9, page (942-947)
Publication Publié, 2004-11
Référence European journal of surgical oncology, 30, 9, page (942-947)
Publication Publié, 2004-11
Article révisé par les pairs
Résumé : | AIM: The aim of this study was to evaluate the role of the 18F-FDG-PET in the preoperative evaluation of patients with oesophageal or gastro-oesophageal junction (GEJ) cancer and to define its impact on therapeutic management. PATIENTS AND METHODS: This study included 58 patients with biopsy proven oesophageal or GEJ cancer who underwent PET in addition to the conventional diagnostic work-up. The sensitivity, specificity and accuracy of CT and PET were calculated for detection of tumour and distant metastases. RESULTS: The sensitivity, specificity and accuracy of tumour detection were, respectively, 84, 100 and 84% for CT and 87, 100 and 87% for PET (p=ns). PET permitted detection of distant metastases, which were not seen on CT in seven patients. In two patients, a second primary tumour was detected on PET. CONCLUSIONS: The sensitivity of PET for loco regional lymph nodes detection is low. The major clinical impact is the detection of distant metastases. |