Titre :
  • To stabilize neutrophil polarity, PIP3 and Cdc42 augment RhoA activity at the back as well as signals at the front.
Auteur : Van Keymeulen, Alexandra ; Wong, Kit ; Knight, Zachary A ; Govaerts, Cédric ; Hahn, Klaus M ; Shokat, Kevan M ; Bourne, Henry R
Informations sur la publication : The Journal of cell biology, 174, 3, (page 437-445)
Statut de publication : Publié, 2006-07
Sujet CREF : Sciences bio-médicales et agricoles
Biochimie
Biologie
Biologie cellulaire
Biologie moléculaire
Biophysique
Sciences biomédicales
Sciences de la matière vivante
Mots-clés MeSH : 1-Phosphatidylinositol 3-Kinase -- antagonists & inhibitors
Bicyclo Compounds, Heterocyclic -- pharmacology
Cell Differentiation -- drug effects
Cell Polarity -- drug effects
Cells, Cultured
Chemotaxis, Leukocyte -- drug effects
HL-60 Cells
Humans
N-Formylmethionine Leucyl-Phenylalanine -- pharmacology
Neutrophils -- cytology
Phenotype
Phosphatidylinositol Phosphates -- metabolism
Phosphorylation -- drug effects
Protein Transport -- drug effects
Pseudopodia -- drug effects
Signal Transduction
Thiazoles -- pharmacology
Thiazolidines
cdc42 GTP-Binding Protein -- metabolism
rhoA GTP-Binding Protein -- metabolism
Note : Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0021-9525 
info:doi/10.1083/jcb.200604113
info:pii/jcb.200604113
info:pmid/16864657