Titre :
  • Apolipoprotein L-I promotes trypanosome lysis by forming pores in lysosomal membranes.
Auteur : Perez-Morga, David ; Vanhollebeke, Benoît ; Hanocq, Françoise ; Nolan, Derek ; Lins, Laurence ; Homble, Fabrice ; Vanhamme, Luc ; Tebabi, Patricia ; Pays Deschutter, Annette ; Poelvoorde, Philippe ; Jacquet, Alain ; Brasseur, Robert ; Pays, Etienne
Informations sur la publication : Science, 309, 5733, (page 469-472)
Statut de publication : Publié, 2005-07
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid -- pharmacology
Amino Acid Sequence
Animals
Anions -- metabolism
Apolipoproteins -- chemistry
Apolipoproteins -- genetics
Apolipoproteins -- metabolism
Apolipoproteins -- pharmacology
Cells, Immobilized
Chlorides -- metabolism
Colicins -- chemistry
Colicins -- pharmacology
Escherichia coli -- drug effects
Escherichia coli -- growth & development
Humans
Intracellular Membranes -- drug effects
Intracellular Membranes -- metabolism
Intracellular Membranes -- ultrastructure
Ion Channels -- metabolism
Lipid Bilayers -- chemistry
Lipoproteins, HDL -- chemistry
Lipoproteins, HDL -- genetics
Lipoproteins, HDL -- metabolism
Lipoproteins, HDL -- pharmacology
Lysosomes -- drug effects
Lysosomes -- metabolism
Lysosomes -- ultrastructure
Models, Molecular
Molecular Sequence Data
Mutation
Permeability
Protein Conformation
Protein Structure, Secondary
Protein Structure, Tertiary
Recombinant Proteins -- metabolism
Trypanosoma brucei brucei -- drug effects
Trypanosoma brucei brucei -- metabolism
Trypanosoma brucei brucei -- ultrastructure
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0036-8075 
info:doi/10.1126/science.1114566
info:pii/309/5733/469
info:pmid/16020735