par Pays, Etienne ;Vanhamme, Luc ;Perez-Morga, David
Référence Current opinion in microbiology, 7, 4, page (369-374)
Publication Publié, 2004-08
Article révisé par les pairs
Résumé : Antigenic variation allows African trypanosomes to develop chronic infections in mammalian hosts. This process results from the alternative occurrence of transcriptional switching and DNA recombination targeted to a telomeric locus that contains the gene of the variant antigen and is subjected to mono-allelic expression control. So far, the identification of mechanisms and factors involved still resists technological developments and genome sequencing.

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