Titre :
  • Cyclic AMP inhibits the proliferation of thyroid carcinoma cell lines through regulation of CDK4 phosphorylation.
Auteur : Rocha, Ana Sofia ; Paternot, Sabine ; Coulonval, Katia ; Dumont, Jacques Emile ; Soares, Paula ; Roger, Pierre P.
Informations sur la publication : Molecular biology of the cell, 19, 11, (page 4814-4825)
Statut de publication : Publié, 2008-11
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Cell Cycle -- drug effects
Cell Line, Tumor
Cell Proliferation -- drug effects
Cyclic AMP -- pharmacology
Cyclic AMP-Dependent Protein Kinases -- metabolism
Cyclin A -- metabolism
Cyclin D
Cyclin-Dependent Kinase 4 -- metabolism
Cyclin-Dependent Kinases -- metabolism
Cyclins -- metabolism
DNA, Neoplasm -- biosynthesis
Enzyme Activation -- drug effects
Extracellular Signal-Regulated MAP Kinases -- metabolism
Forskolin -- pharmacology
Humans
Mutation -- genetics
Phosphorylation -- drug effects
Protein Kinases -- metabolism
Proto-Oncogene Proteins B-raf -- metabolism
Retinoblastoma Protein -- metabolism
Signal Transduction -- drug effects
Thyroid Neoplasms -- enzymology
Thyroid Neoplasms -- pathology
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:1059-1524 
info:doi/10.1091/mbc.E08-06-0617
info:pii/E08-06-0617
info:pmid/18799615
info:pmcid/PMC2575166