Titre :
  • Gene expression profiling in frataxin deficient mice: microarray evidence for significant expression changes without detectable neurodegeneration.
Auteur : Coppola, Giovanni ; Choi, Sang-Hyun ; Santos, M M ; Miranda, C ; Tentler, Dmitri ; Wexler, Eric M ; Pandolfo, Massimo ; Geschwind, Daniel H
Informations sur la publication : Neurobiology of disease, 22, 2, (page 302-311)
Statut de publication : Publié, 2006-05
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés : Frataxin
Friedreich's ataxia
Knockin/knockout
Microarray
Mouse model
Neurodegeneration
Mots-clés MeSH : Animals
Cell Line
Central Nervous System -- metabolism
Central Nervous System -- pathology
Central Nervous System -- physiopathology
Disease Models, Animal
Female
Friedreich Ataxia -- genetics
Friedreich Ataxia -- metabolism
Friedreich Ataxia -- physiopathology
Gene Expression Profiling
Gene Expression Regulation -- genetics
Genetic Predisposition to Disease -- genetics
Humans
Iron-Binding Proteins -- genetics
Male
Mice
Mice, Knockout
Mitochondria -- genetics
Mitochondria -- metabolism
Mutation -- genetics
Nerve Degeneration -- genetics
Nerve Degeneration -- metabolism
Nerve Degeneration -- physiopathology
Oligonucleotide Array Sequence Analysis
Phenotype
Spinal Cord -- metabolism
Spinal Cord -- pathology
Spinal Cord -- physiopathology
Note : Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0969-9961 
info:doi/10.1016/j.nbd.2005.11.014
info:pii/S0969-9961(05)00313-X
info:pmid/16442805