Titre :
  • GGA*TCC-interrupted triplets in long GAA*TTC repeats inhibit the formation of triplex and sticky DNA structures, alleviate transcription inhibition, and reduce genetic instabilities.
Auteur : Sakamoto, N ; Larson, J E ; Iyer, R R ; Montermini, L ; Pandolfo, Massimo ; Wells, R D
Informations sur la publication : The Journal of biological chemistry, 276, 29, (page 27178-27187)
Statut de publication : Publié, 2001-07
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Base Sequence
DNA -- chemistry
DNA Primers
Friedreich Ataxia -- genetics
Mutagenesis, Site-Directed
Nerve Tissue Proteins -- genetics
Nucleic Acid Conformation
Transcription, Genetic
Trinucleotide Repeats
Note : Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Langue :
  • Anglais
Identificateurs : urn:issn:0021-9258 
info:doi/10.1074/jbc.M101852200
info:pii/M101852200
info:pmid/11325966